F11011b02

Anti-Human CD11b, PE （Clone: LT11）检测试剂

¥536.00 – ¥1,200.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

分子靶点：CD11B, MAC-1, ITGAM, CR3A
种属：人 (Human); 小鼠 (Mouse)
标记：PE
亚型：Mouse IgG1
克隆号：LT11

在售SKU, F11011B02/3, 70-F11011B02/3-25, 70-F11011B02/3-100, F11011b02

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Size
库存号

文章目录[隐藏]

结果示例
分子信息
ITGAM 分子靶点信息概述
ITGAM 分子靶点综述

商品名	Anti-Human CD11b, PE （Clone: LT11）检测试剂
靶点	CD11B, MAC-1, ITGAM, CR3A
标记	PE
仪器	适用488nm, 532nm, 561nm激光器的流式细胞仪
亚型	Mouse IgG1
克隆号	LT11
推荐应用	流式检测
用量	5 μL /Test
纯化	亲和层析
储存液	含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃避光，切勿冻存

结果示例

图 - 人外周血染色左图为Mouse IgG1 Isotype control, PE，右图为 Anti-Human CD11b,PE（Clone: LT11）(F11011b02/3) 的结果。以淋巴细胞、粒细胞和单核细胞设门进行分析。

分子信息

概述

ITGAM 分子靶点信息概述

分子名：ITGAM, integrin subunit alpha M
基因家族：CD molecules; Integrin alpha subunits; Complement system regulators and receptors
别名：MAC-1; CD11b
曾用名：CR3A; CD11B
全称：complement component 3 receptor 3 subunit; macrophage-1 antigen alpha subunit; integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide); integrin, alpha M (complement component 3 receptor 3 subunit)

ITGAM 分子靶点综述

整合素αM（ITGAM）是一种形成巨噬细胞抗原（Mac-1）或补体受体3（CR3）的蛋白亚单位。ITGAM又被称为CR3A和分化抗原簇分子11B（CD11b）。CD11b是一种常见的髓系标志物，在急性髓系白血病中有50%的阳性表达率。CD117和CD11b共同检测有助于从恢复良性增殖（CD117阴性表达，CD11b阳性表达）的病例中区分出急性早幼粒细胞白血病（CD11b阴性表达）。