F1103606

Anti-Human CD36, APC-Cyanine7 (Clone: 5-271) (新品)

¥1,312.00 – ¥2,904.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

分子靶点：CD36, FAT, GP4
种属：人 (Human)
标记：APC-Cy7
亚型：Mouse IgG2a, κ
克隆号：5-271

在售SKU, 70-AH03611-20, 70-AH03611-50, 70-AH03611-100, AH03611, 70-F1103606-25, 70-F1103606-100

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Size
库存号

文章目录[隐藏]

结果示例
分子信息
CD36 分子靶点信息概述
CD36 分子靶点综述
- 人 Human CD36 分子靶点信息
- 人 Human CD36靶点分子功能（预测）

商品名	Anti-Human CD36, APC-Cyanine7 (Clone: 5-271)
靶点	CD36, FAT, GP4
标记	APC-Cy7
仪器	适用633nm激光器的流式细胞仪
亚型	Mouse IgG2a, κ
克隆号	5-271
推荐应用	流式检测
用量	5 μL /Test
纯化	亲和层析
储存液	含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃避光，切勿冻存

结果示例

图 - 人外周血染色 Anti-Human CD36, APC-Cyanine7(F1103606)(实线)和对照(虚线)的结果。以血小板设门进行分析。

分子信息

概述人 CD36, FAT, GP4 靶点信息

CD36 分子靶点信息概述

分子名：CD36, CD36 molecule
基因家族：CD molecules; Scavenger receptors
别名：SCARB3; GPIV; FAT; GP4; GP3B
全称：CD36 antigen (collagen type I receptor, thrombospondin receptor); CD36 molecule (thrombospondin receptor)

CD36 分子靶点综述

CD36 是一种 85kDa 的糖蛋白又称 GPIIIb 或 GPI，是胶原和血小板反应素等细胞外基质蛋白的受体。CD36 抗原在单核细胞、血小板、内皮细胞和一些人肿瘤细胞系上表达，但在淋巴细胞和粒细胞上不表达，它是红系分化的早期标志。已知 CD36 介导恶性疟原虫的粘附。CD36 抗体可诱导细胞脱颗粒、释放 ATP和 5-羟色胺、增加[Ca2+]ι,和酪氨酸磷酸化 130k Da 的底物蛋白。CD36 可与血小板反应素、长链脂肪酸、氧化 LDL、胶原 I 型、IV 型和 V 型以及凋亡细胞相结合。

人 Human CD36 分子靶点信息

分子名：CD36, CD36 molecule
别称：
- BDPLT10
- CD36 antigen (collagen type I receptor, thrombospondin receptor)
- CD36 molecule (thrombospondin receptor)
- CHDS7
- cluster determinant 36
- FAT
- fatty acid translocase
- glycoprotein IIIb
- GP3B
- GP4
- GPIIIB
- GPIV
- leukocyte differentiation antigen CD36
- PAS IV
- PAS-4 protein
- PASIV
- platelet glycoprotein 4
- platelet glycoprotein IV
- SCARB3
- scavenger receptor class B, member 3
基因序列：NCBI_Gene: 948
蛋白序列：UniProtKB: P16671

人 Human CD36靶点分子功能（预测）

Enables several functions, including amyloid-beta binding activity; fatty acid transmembrane transporter activity; and low-density lipoprotein particle binding activity. Involved in several processes, including amyloid-beta clearance by cellular catabolic process; lipid transport; and second-messenger-mediated signaling. Located in several cellular components, including Golgi apparatus; cell surface; and membrane raft. Part of receptor complex. Implicated in several diseases, including blood platelet disease (multiple); hemolytic-uremic syndrome; osteoarthritis; pulmonary tuberculosis; and type 2 diabetes mellitus. Biomarker of several diseases, including autoimmune disease (multiple); myeloid neoplasm (multiple); myositis (multiple); rheumatic heart disease; and sickle cell anemia.