F11011B05

Anti-Human/Mouse CD11b，PE-Cy7 (Clone: M1/70) 流式抗体 (新品)

¥480.00 – ¥1,056.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

分子靶点：CD11B, MAC-1, ITGAM, CR3A
种属：人 (Human); 小鼠 (Mouse)
标记：PE-Cy7
亚型：Rat IgG2b, κ
克隆号：M1/70

在售SKU, 70-AH011B10-20, 70-AH011B10-50, 70-AH011B10-100, AH011B10, 70-F11011B05-25, 70-F11011B05-100

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Size
库存号

文章目录[隐藏]

结果示例
分子信息
ITGAM 分子靶点信息概述
ITGAM 分子靶点综述

商品名	Anti-Human/Mouse CD11b，PE-Cy7 (Clone: M1/70) 流式抗体
靶点	CD11B, MAC-1, ITGAM, CR3A
标记	PE-Cy7
仪器	适用488nm, 532nm, 561nm激光器的流式细胞仪
亚型	Rat IgG2b, κ
克隆号	M1/70
推荐应用	流式检测
用量	5 μL /Test
纯化	亲和层析
储存液	含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃避光，切勿冻存

结果示例

图 - 小鼠骨髓细胞染色 Anti-Human/Mouse CD11b, PE-Cy7 (F11011B05) 和 Anti-Human/Mouse CD45R(B220), FITC (F11045R01) 的结果。已排除黏连细胞。

分子信息

概述

ITGAM 分子靶点信息概述

分子名：ITGAM, integrin subunit alpha M
基因家族：CD molecules; Integrin alpha subunits; Complement system regulators and receptors
别名：MAC-1; CD11b
曾用名：CR3A; CD11B
全称：complement component 3 receptor 3 subunit; macrophage-1 antigen alpha subunit; integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide); integrin, alpha M (complement component 3 receptor 3 subunit)

ITGAM 分子靶点综述

CD11b与CD18非共价结合，形成αM-β2整合素(Mac-1)，与CD54(ICAM-1)、C3bi和纤维蛋白原结合。Mac-1表达于巨噬细胞、NK细胞、粒细胞、小胶质细胞、活化的淋巴细胞和小鼠B-1细胞。CD11b与其配体结合，参与粘附细胞的互相作用。此抗体也可交叉识别人CD11b，可检测人外周血中单核细胞、粒细胞和某一群NK细胞上的该抗原。