F1104402

Anti-Human/Mouse CD44 , PE (Clone:IM7) 流式抗体 (新品)

¥424.00 – ¥928.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

分子靶点：CD44, MIC4, CSPG8
种属：人 (Human); 小鼠 (Mouse)
标记：PE
亚型：Rat IgG2b, κ
克隆号：IM7

在售SKU, 70-AH04404-20, 70-AH04404-50, 70-AH04404-100, AH04404, 70-F1104402-25, 70-F1104402-100

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Size
库存号

文章目录[隐藏]

结果示例
分子信息
CD44 分子靶点信息概述
CD44 分子靶点综述

商品名	Anti-Human/Mouse CD44 , PE (Clone:IM7) 流式抗体
靶点	CD44, MIC4, CSPG8
标记	PE
仪器	适用488nm, 532nm, 561nm激光器的流式细胞仪
亚型	Rat IgG2b, κ
克隆号	IM7
推荐应用	流式检测
用量	5 μL /Test
纯化	亲和层析
储存液	含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃避光，切勿冻存

结果示例

图 - 人外周血染色 Anti-Human/Mouse CD44, PE (F1104402 ) 和 Anti-Human CD3, APC (F1100303) 的结果。以 FSC/SSC 中的淋巴细胞设门进行分析。

分子信息

概述

CD44 分子靶点信息概述

分子名：CD44, CD44 molecule (Indian blood group)
基因家族：Blood group antigens; CD molecules; Proteoglycans
别名：IN; MC56; Pgp1; CD44R; HCELL; CSPG8
曾用名：MIC4; MDU2; MDU3
全称：hematopoietic cell E- and L-selectin ligand; chondroitin sulfate proteoglycan 8; CD44 antigen (homing function and Indian blood group system)

CD44 分子靶点综述

CD44为细胞表面的一种糖蛋白，参与细胞-细胞相互作用、细胞黏附和细胞迁移。CD44正常表达在所有的血细胞(血小板除外)和非造血组织，不表达在正常肝细胞，但表达在胆管上皮。CD44异常表达在多发性骨髓瘤细胞、大多数淋巴瘤、慢性淋巴细胞白血病、肿瘤性肥大细胞。CD44主要参与淋巴细胞的激活、参与细胞外基质中的透明质酸、层粘连蛋白等基质分子的结合、介导淋巴细胞与毛细血管后小静脉中的高柱状内皮细胞结合，使淋巴细胞穿过血管壁回到淋巴组织。