F11MPO01

Anti-Human Myeloperoxidase (MPO), FITC (Clone: MPO455-8E6) 检测试剂

¥952.00 – ¥2,112.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

分子靶点：MPO, Myeloperoxidase
种属：人 (Human)
标记：FITC
亚型：Mouse IgG1, κ
克隆号：MPO455-8E6

在售SKU, 70-AH0M01-20, 70-AH0M01-50, 70-AH0M01-100, AH0M01, 70-F11MPO01-25, 70-F11MPO01-100

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Size
库存号

文章目录[隐藏]

结果示例
分子信息
MPO 分子靶点信息概述
MPO 分子靶点综述
- 人 Human MPO 分子靶点信息
- 人 Human MPO靶点分子功能（预测）

商品名	Anti-Human Myeloperoxidase (MPO), FITC (Clone: MPO455-8E6) 检测试剂
靶点	MPO, Myeloperoxidase
标记	FITC
仪器	适用488nm激光器的流式细胞仪
亚型	Mouse IgG1, κ
克隆号	MPO455-8E6
推荐应用	流式检测
用量	5 μL /Test
纯化	亲和层析
储存液	含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃避光，切勿冻存

结果示例

图 - 人外周血经固定破膜后，染色 Anti-Human Myeloperoxidase (MPO), FITC (F11MPO01)的结果。已排除粘连细胞。

分子信息

概述人 MPO, Myeloperoxidase 靶点信息

MPO 分子靶点信息概述

分子名：MPO, myeloperoxidase

MPO 分子靶点综述

髓过氧化物酶(MPO)是一种过氧化物酶，在人类中由位于17号染色体上的MPO基因编码。它是一种存在于中性粒细胞的嗜苯胺蓝颗粒中的溶酶体蛋白，在脱颗粒过程中释放到细胞外空间。MPO在中性粒细胞中表达最丰富，可产生具有抗菌活性的次卤酸。MPO有血红素色素，导致中性粒细胞中的分泌物呈现绿色，如脓。另外，MPO介导蛋白质亚硝基化、3-氯酪氨酸形成及二酪氨酸交联。MPO缺乏症是一种导致机体免疫缺陷的遗传性疾病。MPO水平的升高会大大加倍增加心血管死亡的风险。也有人认为，MPO在动脉粥样硬化病变发展中、致使斑块不稳定中起着重要作用。

人 Human MPO 分子靶点信息

分子名：MPO, myeloperoxidase
别称：
- 无
基因序列：NCBI_Gene: 4353
蛋白序列：UniProtKB: P05164

人 Human MPO靶点分子功能（预测）

Enables heparin binding activity and peroxidase activity. Involved in low-density lipoprotein particle remodeling. Acts upstream of or within hydrogen peroxide catabolic process. Located in azurophil granule; extracellular space; and nucleoplasm. Implicated in several diseases, including Alzheimer's disease 1; cystic fibrosis; kidney failure (multiple); liver disease (multiple); and lung disease (multiple). Biomarker of asthma (multiple); glomerulonephritis; and lung disease (multiple).