F2108603

Anti-Mouse CD86 (B7-2), APC (Clone:GL-1) 流式抗体 (新品)

¥1,080.00 – ¥2,376.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

分子靶点：CD86, B7-2, CD28LG2
种属：小鼠 (Mouse)
标记：APC
亚型：Rat IgG2a, κ
克隆号：GL-1

在售SKU, 70-AM08605-20, 70-AM08605-50, 70-AM08605-100, AM08605, 70-F2108603-25, 70-F2108603-100

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Size
库存号

文章目录[隐藏]

分子信息
CD86 分子靶点信息概述
CD86 分子靶点综述
- 小鼠 Mouse Cd86 分子靶点信息
- 小鼠 Mouse Cd86 靶点分子功能（预测）

商品名	Anti-Mouse CD86 (B7-2), APC (Clone:GL-1) 流式抗体
靶点	CD86, B7-2, CD28LG2
标记	APC
仪器	适用633nm激光器的流式细胞仪
亚型	Rat IgG2a, κ
克隆号	GL-1
推荐应用	流式检测
用量	5 μL /Test
纯化	亲和层析
储存液	含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃避光，切勿冻存

分子信息

概述小鼠 CD86, B7-2, CD28LG2 靶点信息

CD86 分子靶点信息概述

分子名：CD86, CD86 molecule
基因家族：CD molecules; V-set domain containing; B7 family
别名：B7.2; B7-2
曾用名：CD28LG2
全称：B-lymphocyte antigen B7-2; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen)

CD86 分子靶点综述

CD86也称为B7.2，分子量80 kD，表达于树突状细胞、单核细胞、记忆T淋巴细胞、生发中心B淋巴细胞、活化B淋巴细胞以及活化T淋巴细胞。属于免疫球蛋白超家族，其配体是CD28和CD152 (CTLA4)。CD86与诱导剂CD28和抑制剂CTLA4相互作用，是诱导T淋巴细胞增殖及产生IL-2的主要协同因子。

小鼠 Mouse Cd86 分子靶点信息

分子名：Cd86, CD86 antigen
别称：
- B7-2
- B7.2
- B70
- CD28 antigen ligand
- Cd28l2
- Ly-58
- Ly58
- lymphocyte antigen 58
- MB7-2
基因序列：NCBI_Gene: 12524
蛋白序列：

小鼠 Mouse Cd86 靶点分子功能（预测）

Predicted to enable signaling receptor binding activity. Involved in several processes, including CD40 signaling pathway; activation of phospholipase C activity; and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including cellular response to lipopolysaccharide; defense response to virus; and positive regulation of T cell proliferation. Located in external side of plasma membrane and intracellular membrane-bounded organelle. Is expressed in central nervous system and retina. Used to study Guillain-Barre syndrome. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; autoimmune disease (multiple); chronic lymphocytic leukemia; chronic obstructive pulmonary disease; and systemic scleroderma. Orthologous to human CD86 (CD86 molecule).