EK2D5LEG

EasyGo!™ Mouse CD5L One-Step ELISA Kit 检测试剂盒（酶联免疫吸附法）

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在售SKU, EK2D5LEG, 70-EK2D5LEG-96, 70-EK2D5LEG-48

分子靶点：CD5L
种属：小鼠
样本类型：血清，血浆，细胞培养上清及其他生物学样本
检测样本体积：100μL(100倍预稀释)
灵敏度：4.46pg/mL
检测范围：46.88-3000pg/mL
回收率：70%-130%

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Size
库存号

ELISA试剂盒详细信息

商品名	EasyGo!™ Mouse CD5L One-Step ELISA Kit 检测试剂盒（酶联免疫吸附法）
种属	小鼠
靶点	CD5L
检测方法	双抗体夹心法
检测样本类型	血清，血浆，细胞培养上清及其他生物学样本
检测样本体积	100μL(100倍预稀释)
灵敏度	4.46pg/mL
线性范围	46.88-3000pg/mL
精密度	板内变异系数：< 10%;板间变异系数：< 10%
回收率	70%-130%
板式	96孔板，可拆
保存条件	2-8℃
运输条件	2-8℃冰袋运输
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性捕获抗体预包被在高亲和力的酶标板上，酶标板孔中预先加入辣根过氧化物酶标记的检测抗体微球。酶标板孔中加入标准品和待测样本，经过孵育，样本中存在的待测物质与捕获抗体和检测抗体结合。洗涤去除未结合的物质后，加入显色底物（TMB），避光显色。颜色反应的深浅与样本中待测物质的浓度成正比。加入终止液终止反应，在450nm波长 (参考波长570 - 630nm) 测定吸光度值。

文章目录[隐藏]

分子信息
CD5L 分子靶点信息概述
CD5L 分子靶点综述
- 小鼠 Mouse Cd5l 分子靶点信息
- 小鼠 Mouse Cd5l 靶点分子功能（预测）

分子信息

概述小鼠 Cdfl 靶点信息

CD5L 分子靶点信息概述

分子名：CD5L, CD5 molecule like
基因家族：Scavenger receptor cysteine rich domain containing
别名：Spalpha
曾用名：API6
全称：apoptosis inhibitor 6; CD5 antigen-like (scavenger receptor cysteine rich family); CD5 molecule-like

CD5L 分子靶点综述

CD5L（又称CD5抗原样蛋白）是一种可溶性蛋白，属于富含半胱氨酸的清道夫受体（SRCR）超家族B组，包含三个SRCR结构域。该蛋白是一种分泌型糖蛋白，由淋巴组织（脾脏、淋巴结、胸腺和骨髓）中的巨噬细胞表达。它能与髓系单核细胞和淋巴细胞结合，可能在先天性和适应性免疫系统的调控中发挥重要作用。
CD5L作为模式识别分子，既能结合革兰氏阳性菌的脂磷壁酸（LTA），又能结合革兰氏阴性菌的脂多糖（LPS）。其中，CD5L的SRCR结构域1同时保留了这两种结合活性。此外，研究表明CD5L似乎还具有抑制细胞凋亡的作用。

小鼠 Mouse Cd5l 分子靶点信息

分子名：Cd5l, CD5 antigen-like
别称：
- AAC-11
- AI047839
- AIM
- AIM/Spalpha
- Api6
- apoptosis inhibitor 6
- expressed sequence AI047839
- Pdp 1/6
- Sp-alpha
基因序列：NCBI_Gene: 11801
蛋白序列：
- UniprotKB: Q9QWK4

小鼠 Mouse Cd5l 靶点分子功能（预测）

Acts upstream of or within positive regulation of complement-dependent cytotoxicity and regulation of complement activation. Located in cell surface and plasma membrane. Is expressed in several structures, including central nervous system; immune system; liver; retina; and testis. Orthologous to human CD5L (CD5 molecule like).