EK2SA1EG

EasyGo!™ Mouse S100A1 One-Step ELISA Kit 检测试剂盒（酶联免疫吸附法）

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在售SKU, EK2SA1EG, 70-EK2SA1EG-96, 70-EK2SA1EG-48

分子靶点：S100A1
种属：小鼠
样本类型：血清，血浆，细胞培养上清及其他生物学样本
检测样本体积：100μL（100倍预稀释）
灵敏度：4.85pg/mL
检测范围：31.25-2000pg/mL
回收率：70%-130%

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库存号

ELISA试剂盒详细信息

商品名	EasyGo!™ Mouse S100A1 One-Step ELISA Kit 检测试剂盒（酶联免疫吸附法）
种属	小鼠
靶点	S100A1
检测方法	双抗体夹心法
检测样本类型	血清，血浆，细胞培养上清及其他生物学样本
检测样本体积	100μL（100倍预稀释）
灵敏度	4.85pg/mL
线性范围	31.25-2000pg/mL
精密度	板内变异系数：< 10%;板间变异系数：< 10%
回收率	70%-130%
板式	96孔板，可拆
保存条件	2-8℃
运输条件	2-8℃冰袋运输
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性捕获抗体预包被在高亲和力的酶标板上，酶标板孔中预先加入辣根过氧化物酶标记的检测抗体微球。酶标板孔中加入标准品和待测样本，经过孵育，样本中存在的待测物质与捕获抗体和检测抗体结合。洗涤去除未结合的物质后，加入显色底物（TMB），避光显色。颜色反应的深浅与样本中待测物质的浓度成正比。加入终止液终止反应，在450nm波长 (参考波长570 - 630nm) 测定吸光度值。

文章目录[隐藏]

分子信息
S100A1 分子靶点信息概述
S100A1 分子靶点综述
- 小鼠 Mouse S100a1 分子靶点信息
- 小鼠 Mouse S100a1 靶点分子功能（预测）

分子信息

概述小鼠 S100a1 靶点信息

S100A1 分子靶点信息概述

分子名：S100A1, S100 calcium binding protein A1
基因家族：S100 calcium binding proteins; EF-hand domain containing
别名：S100-alpha
曾用名：S100A
全称：S100 calcium-binding protein A1

S100A1 分子靶点综述

S100A1是一种EF-hand型钙离子结合蛋白，属于S100蛋白家族。该家族包含至少19个成员，以二聚体形式广泛存在于多种细胞的胞质或胞核中，参与调控细胞周期进程和分化等多种生理过程。 S100A1在细胞内Ca2+信号传导和平衡方面扮演关键角色，通过调节细胞内Ca2+的稳定状态来影响肿瘤的增殖和免疫逃避能力。研究表明，S100A1的表达水平与肿瘤的免疫治疗响应密切相关。低表达S100A1的患者通常对免疫治疗反应更好，总生存期更长。此外，S100A1还参与微管组装和蛋白质磷酸化，这些过程对其在细胞内的功能至关重要。

小鼠 Mouse S100a1 分子靶点信息

分子名：S100a1, S100 calcium binding protein A1
别称：
- AI266795
- expressed sequence AI266795
- S100
- S100a
基因序列：NCBI_Gene: 20193
蛋白序列：

小鼠 Mouse S100a1 靶点分子功能（预测）

Predicted to enable several functions, including ATPase binding activity; S100 protein binding activity; and protein homodimerization activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of nitric-oxide synthase activity; and positive regulation of sprouting angiogenesis. Located in sarcoplasmic reticulum. Is expressed in several structures, including brain; heart; inner ear; musculature; and urothelium. Orthologous to human S100A1 (S100 calcium binding protein A1).