EK1313

Human BMP-9 ELISA Kit检测试剂盒（酶联免疫吸附法）

¥1,600.00 – ¥2,650.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

在售SKU:70-EK1313-48, 70-EK1313-96, EK1313

分子靶点：GDF2
种属：人
样本类型：血清、血浆、细胞培养上清及其他生物学样本
检测样本体积：血清、血浆样本50μL
灵敏度：0.19pg/mL
检测范围：7.81-500pg/mL
回收率：75%-118%

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Size
库存号

ELISA试剂盒详细信息

商品名	Human BMP-9 ELISA Kit检测试剂盒（酶联免疫吸附法）
种属	人
靶点	GDF2
检测方法	双抗体夹心法
检测样本类型	血清、血浆、细胞培养上清及其他生物学样本
检测样本体积	血清、血浆样本50μL
灵敏度	0.19pg/mL
线性范围	7.81-500pg/mL
精密度	板内变异系数：3.0%-4.3%;板间变异系数：0.9%-4.4%
回收率	75%-118%
平均回收率	102%
板式	96孔板，可拆
保存条件	2-8℃保存。已拆开：标准品-20℃保存，其它4℃。
运输条件	2-8℃冰袋运输
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性捕获抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的待测物质与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中待测物质的浓度成正比。加入终止液终止反应，在450nm波长(参考波长570 - 630nm)测定吸光度值。

文章目录[隐藏]

分子信息
GDF2 分子靶点信息概述
GDF2 分子靶点综述
- 人 Human GDF2 分子靶点信息
- 人 Human GDF2靶点分子功能（预测）

分子信息

概述人 GDF2, BMP9 靶点信息

GDF2 分子靶点信息概述

分子名：GDF2, growth differentiation factor 2
基因家族：Transforming growth factor beta superfamily
别名：BMP-9; BMP9

GDF2 分子靶点综述

人骨形成蛋白9 (BMP-9)又称生长分化因子2 (GDF-2)，是转化生长因子β超家族蛋白BMP亚群的一员，通过由Ⅰ型和Ⅱ型BMP受体组成的异二聚体复合物传递信号。BMP-9调节多种胚胎和成体组织的发育和功能。BMP-9由肝脏非实质细胞合成分泌，它能促进脂质代谢并抑制葡萄糖生成。在胚胎中枢神经系统中，BMP-9在胆碱能神经元表型的发育和维持中起着重要作用。BMP-9也诱导间充质干细胞分化为软骨细胞系。在低浓度时，BMP-9是造血祖细胞的增殖因子；但在高浓度时，它会促进TGF-β1的产生并抑制造血祖细胞集落的形成。

人 Human GDF2 分子靶点信息

分子名：GDF2, growth differentiation factor 2
别称：
- BMP-9
- BMP9
- bone morphogenetic protein 9
- GDF-2
- growth/differentiation factor 2
- HHT5
基因序列：NCBI_Gene: 2658
蛋白序列：UniProtKB: Q9UK05

人 Human GDF2靶点分子功能（预测）

Predicted to enable cytokine activity. Involved in several processes, including positive regulation of macromolecule metabolic process; regulation of endothelial cell proliferation; and transmembrane receptor protein serine/threonine kinase signaling pathway. Located in extracellular exosome. Implicated in hereditary hemorrhagic telangiectasia.