EK1130

Human CCL11/Eotaxin ELISA Kit检测试剂盒（酶联免疫吸附法）

¥1,600.00 – ¥2,650.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

在售SKU:70-EK1130-48, 70-EK1130-96, EK1130

分子靶点：CCL11
种属：人
样本类型：血清、血浆、细胞培养上清及其他生物学样本
检测样本体积：血清、血浆样本50μL
灵敏度：3.14pg/mL
检测范围：15.63-1000pg/mL
回收率：82%-107%

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Size
库存号

ELISA试剂盒详细信息

商品名	Human CCL11/Eotaxin ELISA Kit检测试剂盒（酶联免疫吸附法）
种属	人
靶点	CCL11
检测方法	双抗体夹心法
检测样本类型	血清、血浆、细胞培养上清及其他生物学样本
检测样本体积	血清、血浆样本50μL
灵敏度	3.14pg/mL
线性范围	15.63-1000pg/mL
精密度	板内变异系数：4.5%-6.5%;板间变异系数：5.9%-8.1%
回收率	82%-107%
平均回收率	90%
板式	96孔板，可拆
保存条件	2-8℃保存。已拆开：标准品-20℃保存，其它4℃。
运输条件	2-8℃冰袋运输
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人CCL11抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的CCL11与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中CCL11的浓度成正比。加入终止液终止反应，在450nm波长(参考波长570 - 630nm)测定吸光度值。

文章目录[隐藏]

分子信息
CCL11 分子靶点信息概述
CCL11 分子靶点综述
- 人 Human CCL11 分子靶点信息
- 人 Human CCL11靶点分子功能（预测）

分子信息

概述人 CCL11, Eotaxin, SCYA11 靶点信息

CCL11 分子靶点信息概述

分子名：CCL11, C-C motif chemokine ligand 11
基因家族：Chemokine ligands
别名：eotaxin; MGC22554
曾用名：SCYA11
全称：eotaxin-1; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin); chemokine (C-C motif) ligand 11

CCL11 分子靶点综述

趋化因子配体11(CCL11)也称为嗜酸性粒细胞趋化因子(Eotaxin)，是CC趋化因子家族中的小分子量细胞因子。Eotaxin通过诱导嗜酸性粒细胞的趋化性进行选择性招募，因此参与变态反应。Eotaxin在人和小鼠血浆中的表达升高与其衰老有关。相比于曾经吸食大麻者和从未吸食大麻者，目前仍在吸食大麻者的血浆中含有更高浓度的Eotaxin。精神分裂者体内的Eotaxin浓度也更高，而大麻正是已知的精神分裂症诱导剂。

人 Human CCL11 分子靶点信息

分子名：CCL11, C-C motif chemokine ligand 11
别称：
- C-C motif chemokine 11
- chemokine (C-C motif) ligand 11
- eosinophil chemotactic protein
- eotaxin
- eotaxin-1
- MGC22554
- SCYA11
- small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
- small-inducible cytokine A11
基因序列：NCBI_Gene: 6356
蛋白序列：UniProtKB: P51671

人 Human CCL11靶点分子功能（预测）

Enables CCR3 chemokine receptor binding activity; chemokine activity; and protein dimerization activity. Involved in several processes, including eosinophil chemotaxis; positive regulation of GTPase activity; and positive regulation of actin filament polymerization. Located in extracellular region. Implicated in asthma; human immunodeficiency virus infectious disease; and hyperglycemia. Biomarker of several diseases, including cystic fibrosis; hyperglycemia; lung disease (multiple); nephrotic syndrome type 1; and ureteral obstruction.