EK1288

Human CCL16/HCC-4/NCC-4 ELISA Kit检测试剂盒（酶联免疫吸附法）

¥1,600.00 – ¥2,650.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

在售SKU:70-EK1288-48, 70-EK1288-96, EK1288

分子靶点：CCL16
种属：人
样本类型：血清、血浆、细胞培养上清及其他生物学样本
检测样本体积：血清、血浆样本10μL
灵敏度：1.38pg/mL
检测范围：7.81-500pg/mL
回收率：88%-109%

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Size
库存号

ELISA试剂盒详细信息

商品名	Human CCL16/HCC-4/NCC-4 ELISA Kit检测试剂盒（酶联免疫吸附法）
种属	人
靶点	CCL16
检测方法	双抗体夹心法
检测样本类型	血清、血浆、细胞培养上清及其他生物学样本
检测样本体积	血清、血浆样本10μL
灵敏度	1.38pg/mL
线性范围	7.81-500pg/mL
精密度	板内变异系数：2.5%-4.8%;板间变异系数：2.5%-4.8%
回收率	88%-109%
平均回收率	96%
板式	96孔板，可拆
保存条件	2-8℃保存。已拆开：标准品-20℃保存，其它4℃。
运输条件	2-8℃冰袋运输
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人CCL16抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的CCL16与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中CCL16的浓度成正比。加入终止液终止反应，在450nm波长(参考波长570 - 630nm)测定吸光度值。

文章目录[隐藏]

分子信息
CCL16 分子靶点信息概述
CCL16 分子靶点综述
- 人 Human CCL16 分子靶点信息
- 人 Human CCL16靶点分子功能（预测）

分子信息

概述人 CCL16, HCC-4, NCC-4, LEC 靶点信息

CCL16 分子靶点信息概述

分子名：CCL16, C-C motif chemokine ligand 16
基因家族：Chemokine ligands
别名：NCC-4; SCYL4; LEC; HCC-4; LMC; LCC-1; CKb12; Mtn-1
曾用名：SCYA16
全称：small inducible cytokine subfamily A (Cys-Cys), member 16; chemokine (C-C motif) ligand 16

CCL16 分子靶点综述

趋化因子CC配体16(CCL16)是CC趋化因子家族中的小分子细胞因子，也称为NCC-4、肝脏表达趋化因子(LEC)、以及淋巴细胞和单核细胞趋化因子(LMC)。这种趋化因子由肝脏、胸腺和脾脏表达，对单核细胞和淋巴细胞具有趋化性。在单核细胞中可以通过IL-10、IFN-γ和细菌脂多糖强烈诱导CCL16的细胞表达。此外，CCL16通过与细胞表面趋化因子受体 (如CCR1、CCR2、CCR5和CCR8 ) 相互作用而引发其对细胞的影响。该趋化因子会抑制骨髓前体细胞的快速增殖。

人 Human CCL16 分子靶点信息

分子名：CCL16, C-C motif chemokine ligand 16
别称：
- C-C motif chemokine 16
- chemokine (C-C motif) ligand 16
- chemokine CC-4
- chemokine LEC
- CKb12
- HCC-4
- IL-10-inducible chemokine
- ILINCK
- LCC-1
- LEC
- liver CC chemokine-1
- liver-expressed chemokine
- LMC
- lymphocyte and monocyte chemoattractant
- MGC117051
- monotactin-1
- Mtn-1
- NCC-4
- NCC4
- new CC chemokine 4
- SCYA16
- SCYL4
- small inducible cytokine subfamily A (Cys-Cys), member 16
- small-inducible cytokine A16
基因序列：NCBI_Gene: 6360
蛋白序列：UniProtKB: O15467

人 Human CCL16靶点分子功能（预测）

Enables chemoattractant activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; leukocyte chemotaxis; and positive regulation of ERK1 and ERK2 cascade. Predicted to be located in extracellular region. Predicted to be active in extracellular space.