EK1174

Human Fetuin-A ELISA Kit检测试剂盒（酶联免疫吸附法）

¥1,600.00 – ¥2,650.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

在售SKU:70-EK1174-48, 70-EK1174-96, EK1174

分子靶点：AHSG
种属：人
样本类型：血清、血浆、细胞培养上清及其他生物学样本
检测样本体积：血清、血浆样本10μL
灵敏度：2.22pg/mL
检测范围：46.88-3000pg/mL
回收率：88%-110%

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Size
库存号

ELISA试剂盒详细信息

商品名	Human Fetuin-A ELISA Kit检测试剂盒（酶联免疫吸附法）
种属	人
靶点	AHSG
检测方法	双抗体夹心法
检测样本类型	血清、血浆、细胞培养上清及其他生物学样本
检测样本体积	血清、血浆样本10μL
灵敏度	2.22pg/mL
线性范围	46.88-3000pg/mL
精密度	板内变异系数：4.9%-5.1%;板间变异系数：2.3%-5.4%
回收率	88%-110%
平均回收率	103%
板式	96孔板，可拆
保存条件	2-8℃保存。已拆开：标准品-20℃保存，其它4℃。
运输条件	2-8℃冰袋运输
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性捕获抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的待测物质与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中待测物质的浓度成正比。加入终止液终止反应，在450nm波长(参考波长570 - 630nm)测定吸光度值。

文章目录[隐藏]

分子信息
AHSG 分子靶点信息概述
AHSG 分子靶点综述
- 人 Human AHSG 分子靶点信息
- 人 Human AHSG靶点分子功能（预测）

分子信息

概述人 AHSG, Fetuin-A 靶点信息

AHSG 分子靶点信息概述

分子名：AHSG, alpha 2-HS glycoprotein
基因家族：Cystatins, type 4
别名：FETUA; A2HS; HSGA
全称：fetuin A

AHSG 分子靶点综述

胎球蛋白是由肝脏产生，分泌到血液中的蛋白。它们属于介导血液中各种物质的转运和利用的结合蛋白。人胎球蛋白也称为α2-HS糖蛋白(AHSG)、α2-HS、A2HS、AHS、HSGA和胎球蛋白A。基因敲除小鼠的实验表明，胎球蛋白A是潜在的全身性钙化抑制剂。它对肝脏中游离脂肪酸诱导的胰岛素耐受具有重要作用。在糖尿病前期，胎球蛋白A可预测不良血糖的结果。它也与非酒精性脂肪肝和心血管疾病发病率升高有关。在脓毒病和内毒素血症中，它是负性急性期反应物，促进伤口愈合，对阿尔茨海默病具有神经保护作用。在阻塞性肺疾病、克罗恩病和溃疡性结肠炎中，胎球蛋白A水平下降，预示着疾病活跃的风险增加。

人 Human AHSG 分子靶点信息

分子名：AHSG, alpha 2-HS glycoprotein
别称：
- A2HS
- AHS
- alpha-2-HS-glycoprotein
- alpha-2-Z-globulin
- APMR1
- ba-alpha-2-glycoprotein
- FETUA
- fetuin A
- fetuin-A
- HSGA
基因序列：NCBI_Gene: 197
蛋白序列：UniProtKB: P02765

人 Human AHSG靶点分子功能（预测）

Predicted to enable endopeptidase inhibitor activity. Involved in acute-phase response; positive regulation of phagocytosis; and regulation of inflammatory response. Located in Golgi apparatus. Implicated in alopecia-mental retardation syndrome 1; coronary artery disease; and type 2 diabetes mellitus. Biomarker of gestational diabetes; myocardial infarction; obesity; and type 2 diabetes mellitus.