EK1167

Human Leptin R ELISA Kit检测试剂盒（酶联免疫吸附法）

¥1,600.00 – ¥2,650.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

在售SKU:70-EK1167-48, 70-EK1167-96, EK1167, 人瘦素受体人瘦素受体瘦素受体

分子靶点：LEPR
种属：人
样本类型：血清、血浆、细胞培养上清及其他生物学样本
检测样本体积：血清、血浆样本10μL
灵敏度：3.26pg/mL
检测范围：62.5-4000pg/mL
回收率：82%-118%

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Size
库存号

ELISA试剂盒详细信息

商品名	Human Leptin R ELISA Kit检测试剂盒（酶联免疫吸附法）
种属	人
靶点	LEPR
检测方法	双抗体夹心法
检测样本类型	血清、血浆、细胞培养上清及其他生物学样本
检测样本体积	血清、血浆样本10μL
灵敏度	3.26pg/mL
线性范围	62.5-4000pg/mL
精密度	板内变异系数：4.3%-4.6%;板间变异系数：3.2%-4%
回收率	82%-118%
平均回收率	98%
板式	96孔板，可拆
保存条件	2-8℃保存。已拆开：标准品-20℃保存，其它4℃。
运输条件	2-8℃冰袋运输
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人LeptinR抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的LeptinR与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中LeptinR的浓度成正比。加入终止液终止反应，在450nm波长(参考波长570 - 630nm)测定吸光度值。

文章目录[隐藏]

分子信息
LEPR 分子靶点信息概述
LEPR 分子靶点综述
- 人 Human LEPR 分子靶点信息
- 人 Human LEPR靶点分子功能（预测）

分子信息

概述人 LEPR, CD295 靶点信息

LEPR 分子靶点信息概述

分子名：LEPR, leptin receptor
基因家族：CD molecules; Immunoglobulin like domain containing
别名：OBR; CD295

LEPR 分子靶点综述

瘦素受体 (Leptin R)也称为OB-R或CD295，在人类中，由LEPR基因编码。它作为脂肪细胞特异性荷尔蒙瘦素的受体发挥作用。通过下丘脑对饥饿和能量消耗的作用，瘦素与其受体结合后调控脂肪组织块。瘦素受体的变异与糖尿病和对溶组织阿米巴感染易感性升高有关。

人 Human LEPR 分子靶点信息

分子名：LEPR, leptin receptor
别称：
- CD295
- DKFZp686B1731
- huB219
- LEP-R
- LEPRD
- OB receptor
- OB-R
- OBR
基因序列：NCBI_Gene: 3953
蛋白序列：UniProtKB: P48357

人 Human LEPR靶点分子功能（预测）

Enables identical protein binding activity and leptin receptor activity. Involved in several processes, including angiogenesis; leptin-mediated signaling pathway; and negative regulation of autophagy. Part of receptor complex. Implicated in several diseases, including artery disease (multiple); non-alcoholic fatty liver disease (multiple); obesity; obstructive sleep apnea; and type 2 diabetes mellitus. Biomarker of arteriosclerosis; chronic obstructive pulmonary disease; human immunodeficiency virus infectious disease; liver disease (multiple); and sleep apnea.