EK1358

Human LYVE-1 ELISA Kit检测试剂盒（酶联免疫吸附法）

¥2,200.00 – ¥3,700.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

在售SKU:70-EK1358-48, 70-EK1358-96, EK1358

分子靶点：LYVE1
种属：人
样本类型：血清、血浆、细胞培养上清及其他生物学样本
检测样本体积：血清、血浆样本5μL
灵敏度：2.01pg/mL
检测范围：31.25-2000pg/mL
回收率：86%-105%

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Size
库存号

ELISA试剂盒详细信息

商品名	Human LYVE-1 ELISA Kit检测试剂盒（酶联免疫吸附法）
种属	人
靶点	LYVE1
检测方法	双抗体夹心法
检测样本类型	血清、血浆、细胞培养上清及其他生物学样本
检测样本体积	血清、血浆样本5μL
灵敏度	2.01pg/mL
线性范围	31.25-2000pg/mL
精密度	板内变异系数：2.9%-3.8%;板间变异系数：3.8%-4.9%
回收率	86%-105%
平均回收率	95%
板式	96孔板，可拆
保存条件	2-8℃保存。已拆开：标准品-20℃保存，其它4℃。
运输条件	2-8℃冰袋运输
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人LYVE-1抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的LYVE-1与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中LYVE-1的浓度成正比。加入终止液终止反应，在450nm波长(参考波长570 - 630nm)测定吸光度值。

文章目录[隐藏]

分子信息
LYVE1 分子靶点信息概述
LYVE1 分子靶点综述
- 人 Human LYVE1 分子靶点信息
- 人 Human LYVE1靶点分子功能（预测）

分子信息

概述人 LYVE1, XLKD1 靶点信息

LYVE1 分子靶点信息概述

分子名：LYVE1, lymphatic vessel endothelial hyaluronan receptor 1
别名：LYVE-1
曾用名：XLKD1
全称：extracellular link domain containing 1

LYVE1 分子靶点综述

淋巴管内皮透明质酸受体-1（LYVE-1）作为淋巴管内皮特异性标志物，特异性地表达于淋巴内皮细胞，均匀分布于淋巴管内皮细胞的基底面和胞腔面，其广泛地应用促进肿瘤淋巴转移领域的研究。近年来，LYVE-1本身的生物学功能及其在肿瘤转移领域中发挥的作用已成为肿瘤转移的研究热点之一。阐明LYVE-1在肿瘤淋巴转移中的作用机制，对于建立肿瘤治疗新方法有着重大的意义。

人 Human LYVE1 分子靶点信息

分子名：LYVE1, lymphatic vessel endothelial hyaluronan receptor 1
别称：
- cell surface retention sequence binding protein-1
- cell surface retention sequence-binding protein 1
- CRSBP-1
- extracellular link domain containing 1
- extracellular link domain-containing 1
- extracellular link domain-containing protein 1
- HAR
- hyaluronic acid receptor
- lymphatic vessel endothelial hyaluronic acid receptor 1
- LYVE-1
- XLKD1
基因序列：NCBI_Gene: 10894
蛋白序列：UniProtKB: Q9Y5Y7

人 Human LYVE1靶点分子功能（预测）

Predicted to enable hyaluronic acid binding activity and transmembrane signaling receptor activity. Predicted to be involved in anatomical structure morphogenesis; cell-matrix adhesion; and response to wounding. Predicted to act upstream of or within glycosaminoglycan catabolic process. Located in extracellular exosome.