EK1312

Human sICAM-3/CD50 ELISA Kit检测试剂盒（酶联免疫吸附法）

¥1,600.00 – ¥2,650.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

在售SKU:70-EK1312-48, 70-EK1312-96, EK1312

分子靶点：ICAM3
种属：人
样本类型：血清、血浆、细胞培养上清及其他生物学样本
检测样本体积：血清、血浆样本10μL
灵敏度：5.09pg/mL
检测范围：125-8000pg/mL
回收率：77%-112%

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Size
库存号

ELISA试剂盒详细信息

商品名	Human sICAM-3/CD50 ELISA Kit检测试剂盒（酶联免疫吸附法）
种属	人
靶点	ICAM3
检测方法	双抗夹心法
检测样本类型	血清、血浆、细胞培养上清及其他生物学样本
检测样本体积	血清、血浆样本10μL
灵敏度	5.09pg/mL
线性范围	125-8000pg/mL
精密度	板内变异系数：2.5%-3.9%;板间变异系数：1.6%-6.2%
回收率	77%-112%
平均回收率	93%
板式	96孔板，可拆
保存条件	2-8℃保存。已拆开：标准品-20℃保存，其它4℃。
运输条件	2-8℃冰袋运输
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性捕获抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和辣根过氧化物酶标记的检测抗体，经过孵育，样本中存在的待测物质与捕获抗体和检测抗体结合。洗涤后，加入显色底物（TMB），避光显色。颜色反应的深浅与样本中待测物质的浓度成正比。加入终止液终止反应，在450nm波长（参考波长570 - 630nm）测定吸光度值。

文章目录[隐藏]

分子信息
ICAM3 分子靶点信息概述
ICAM3 分子靶点综述
- 人 Human ICAM3 分子靶点信息
- 人 Human ICAM3靶点分子功能（预测）

分子信息

概述人 ICAM3, ICAM-R, CD50 靶点信息

ICAM3 分子靶点信息概述

分子名：ICAM3, intercellular adhesion molecule 3
基因家族：CD molecules; Immunoglobulin like domain containing; Ig-like cell adhesion molecule family
别名：CDW50; ICAM-R; CD50

ICAM3 分子靶点综述

细胞间粘附分子3 (ICAM-3)，也称为CD50，是免疫球蛋白超家族的成员，可与白细胞整合素LFA-1 (CD11a/CD18)和αd/β2结合。ICAM-3在白细胞和表皮朗格汉斯细胞上表达。ICAM-3是一种由白细胞表达的跨膜糖蛋白，是淋巴细胞功能相关抗原(LFA)-1整合素的反受体。ICAM-3除了作为T细胞与抗原呈递细胞接触的粘附分子外，还可调节LFA-1对ICAM-1的亲和力，并诱导T细胞活化和增殖。ICAM-3在T细胞和抗原呈递细胞的免疫应答启动过程中发挥重要作用。CD50分子在T淋巴细胞功能成熟过程中发挥作用，在T淋巴细胞成熟过程中表达增多。