EK224

Mouse IL-24 ELISA Kit检测试剂盒（酶联免疫吸附法）

Name: Mouse IL-24 ELISA Kit检测试剂盒（酶联免疫吸附法）
SKU: EK224
Availability: InStock

¥1,600.00 – ¥2,650.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

在售SKU:70-EK224-48, 70-EK224-96, EK224

分子靶点：IL24
种属：小鼠
样本类型：血清、血浆、细胞培养上清及其他生物学样本
检测样本体积：血清血浆：100μL；细胞培养上清：100μL
灵敏度：6.48pg/mL
检测范围：7.81-500pg/mL
回收率：85%-119%

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Size
库存号

ELISA试剂盒详细信息

商品名	Mouse IL-24 ELISA Kit检测试剂盒（酶联免疫吸附法）
种属	小鼠
靶点	IL24
检测方法	双抗体夹心法
检测样本类型	血清、血浆、细胞培养上清及其他生物学样本
检测样本体积	血清血浆：100μL；细胞培养上清：100μL
灵敏度	6.48pg/mL
线性范围	7.81-500pg/mL
精密度	板内变异系数：8.2%-9.4%;板间变异系数：3.3%-9.4%
回收率	85%-119%
平均回收率	97%
板式	96孔板，可拆
保存条件	2-8℃保存。已拆开：标准品-20℃保存，其它4℃。
运输条件	2-8℃冰袋运输
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗小鼠IL-24抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的IL-24与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中IL-24的浓度成正比。加入终止液终止反应，在450nm波长(参考波长570 - 630nm)测定吸光度值。

文章目录[隐藏]

分子信息
IL24 分子靶点信息概述
IL24 分子靶点综述
- 小鼠 Mouse Il24 分子靶点信息
- 小鼠 Mouse Il24 靶点分子功能（预测）

分子信息

概述小鼠 IL24, ST16, IL-24 靶点信息

IL24 分子靶点信息概述

分子名：IL24, interleukin 24
基因家族：Interleukins
别名：ST16; mda-7; IL10B; Mob-5; C49A; FISP; IL-24
全称：melanoma differentiation association protein 7; suppression of tumorigenicity 16 (melanoma differentiation); IL-4-induced secreted protein

IL24 分子靶点综述

白细胞介素24(Interleukin 24, IL-24)是属于IL-10细胞因子家族的细胞因子，通过 IL-20R1/IL-20R2和IL-22R1/IL-20R2两个异源二聚体受体进行信号传导。IL-24可能通过诱导特定的转录因子Stat-1和Stat-3快速激活来控制细胞存活和增殖。小鼠IL24表达约35kD的蛋白，通过去糖基化转化为一个23kD的蛋白。IL24蛋白与IL10细胞因子家族的其他成员具有24-33%的同源性，与IL20的同源性最高。
该细胞因子主要由活化的单核细胞、巨噬细胞和辅助T细胞(Th2)释放，并作用于皮肤、肺和生殖组织等非造血组织。IL-24在伤口愈合、银屑病和癌症治疗中发挥重要作用。

小鼠 Mouse Il24 分子靶点信息

分子名：Il24, interleukin 24
别称：
- FISP
- Mda-7
基因序列：NCBI_Gene: 93672
蛋白序列：

小鼠 Mouse Il24 靶点分子功能（预测）

Predicted to enable cytokine activity. Acts upstream of or within negative regulation of cell population proliferation; positive regulation of apoptotic process; and regulation of cysteine-type endopeptidase activity involved in apoptotic process. Located in endoplasmic reticulum and extracellular region. Is expressed in alimentary system; brain; gonad; hemolymphoid system gland; and metanephros. Orthologous to human IL24 (interleukin 24).