F11011C03

Anti-Human CD11c, APC (Clone:3.9)检测试剂

¥872.00 – ¥1,936.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

分子靶点：CD11C, ITGAX
种属：人 (Human)
标记：APC
亚型：Mouse IgG1, κ
克隆号：3.9

在售SKU, 70-AH011C05-20, 70-AH011C05-50, 70-AH011C05-100, AH011C05, 70-F11011C03-25, 70-F11011C03-100

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Size
库存号

文章目录[隐藏]

结果示例
分子信息
ITGAX 分子靶点信息概述
ITGAX 分子靶点综述
- 人 Human ITGAX 分子靶点信息
- 人 Human ITGAX靶点分子功能（预测）

商品名	Anti-Human CD11c, APC (Clone:3.9)检测试剂
靶点	CD11C, ITGAX
标记	APC
仪器	适用633nm激光器的流式细胞仪
亚型	Mouse IgG1, κ
克隆号	3.9
推荐应用	流式检测
用量	5 μL /Test
纯化	亲和层析
储存液	含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃避光，切勿冻存

结果示例

图 - 人外周血染色 Anti-Human CD11c, APC (F11011C03) 和 Anti-Human CD14, FITC (F1101401) 的结果。以FSC/SSC 中的淋巴细胞和单核细胞设门进行分析。

分子信息

概述人 CD11C, ITGAX 靶点信息

ITGAX 分子靶点信息概述

分子名：ITGAX, integrin subunit alpha X
基因家族：CD molecules; Integrin alpha subunits; Complement system regulators and receptors
别名：CD11c
曾用名：CD11C
全称：complement component 3 receptor 4 subunit; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit)

ITGAX 分子靶点综述

CD11c被称为补体受体4 (Complement receptor, CR4)，是黏附分子CD11/CD18家族中的一员，属于I型跨膜糖蛋白，高表达于髓系DCs表面。CD11c作为一正性调控因子，参与DCs的黏附、迁移，抗原的识别和呈递，并激活CD4+、CD8+ T细胞，调控免疫应答发生，在感染和抗肿瘤免疫中发挥重要作用。

人 Human ITGAX 分子靶点信息

分子名：ITGAX, integrin subunit alpha X
别称：
- CD11 antigen-like family member C
- CD11C
- complement component 3 receptor 4 subunit
- integrin alpha X
- integrin alpha-X
- integrin, alpha X (antigen CD11C (p150), alpha polypeptide)
- integrin, alpha X (complement component 3 receptor 4 subunit)
- leu M5, alpha subunit
- leukocyte adhesion glycoprotein p150,95 alpha chain
- leukocyte adhesion receptor p150,95
- leukocyte surface antigen p150,95, alpha subunit
- myeloid membrane antigen, alpha subunit
- p150 95 integrin alpha chain
- SLEB6
基因序列：NCBI_Gene: 3687
蛋白序列：UniProtKB: P20702

人 Human ITGAX靶点分子功能（预测）

Enables receptor tyrosine kinase binding activity. Involved in several processes, including heterotypic cell-cell adhesion; positive regulation of angiogenesis; and positive regulation of endothelial tube morphogenesis. Located in cell surface.