F1116302

Anti-Human CD163, PE （Clone: R20）流式抗体检测试剂

¥1,256.00 – ¥2,760.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

分子靶点：CD163
种属：人 (Human)
标记：PE
亚型：Mouse IgG1
克隆号：R20

在售SKU, F1116302, 70-F1116302-25, 70-F1116302-100

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Size
库存号

文章目录[隐藏]

结果示例
分子信息
CD163 分子靶点信息概述
CD163 分子靶点综述
- 人 Human CD163 分子靶点信息
- 人 Human CD163靶点分子功能（预测）

商品名	Anti-Human CD163, PE （Clone: R20）检测试剂
标记	PE
仪器	适用488nm, 532nm, 561nm激光器的流式细胞仪
亚型	Mouse IgG1
克隆号	R20
推荐应用	流式检测
用量	5 μL /Test
纯化	亲和层析
储存液	含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃避光，切勿冻存

结果示例

图 - 人外周血染色 Anti-Human CD163, PE（Clone: R20） (F1116302) 和 Anti-Human CD11b, APC的结果。
以单核细胞设门进行分析。

分子信息

概述人 CD163 靶点信息

CD163 分子靶点信息概述

分子名：CD163, CD163 molecule
基因家族：CD molecules; Scavenger receptors; Scavenger receptor cysteine rich domain containing
别名：M130; MM130; SCARI1
全称：CD163 antigen

CD163 分子靶点综述

CD163 是 I 型膜蛋白，是血红蛋白清道夫受体富含半胱氨酸超家族的成员。该蛋白质参与血红蛋白-触珠蛋白复合物的清除，被认为具有抗炎功能。CD163也是单核细胞/巨噬细胞谱系细胞的标志物，它在所有的循环单核细胞和大部分的组织巨噬细胞中表达，如脾脏的树突状细胞、肺泡巨噬细胞和肝脏的库普弗细胞，而不存在于淋巴滤泡区的巨噬细胞、树突状细胞、朗格汉斯细胞。CD163可用于肿瘤和反应性病变中单核细胞和组织细胞的检测。在检测巨噬细胞和单核细胞时，它比CD68更敏感。

人 Human CD163 分子靶点信息

分子名：CD163, CD163 molecule
别称：
- cluster of differentiation 163
- hemoglobin scavenger receptor
- M130
- macrophage-associated antigen
- MM130
- SCARI1
- scavenger receptor cysteine-rich type 1 protein M130
基因序列：NCBI_Gene: 9332
蛋白序列：UniProtKB: Q86VB7

人 Human CD163靶点分子功能（预测）

Enables scaffold protein binding activity. Predicted to be involved in acute-phase response and endocytosis. Located in external side of plasma membrane. Biomarker of several diseases, including Ebola hemorrhagic fever; Whipple disease; fatty liver disease (multiple); leishmaniasis (multiple); and lung disease (multiple).