F11FP302

Anti-Human FoxP3, PE (Clone:PCH101)流式抗体 (新品)

¥1,192.00 – ¥2,640.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

分子靶点：FOXP3, IPEX
种属：人 (Human)
标记：PE
亚型：Rat IgG2a, κ
克隆号：PCH101

在售SKU, 70-AH0F04-20, 70-AH0F04-50, 70-AH0F04-100, AH0F04, 70-F11FP302-25, 70-F11FP302-100

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Size
库存号

文章目录[隐藏]

结果示例
分子信息
FOXP3 分子靶点信息概述
FOXP3 分子靶点综述
- 人 Human FOXP3 分子靶点信息
- 人 Human FOXP3靶点分子功能（预测）

商品名	Anti-Human FoxP3, PE (Clone:PCH101)流式抗体
靶点	FOXP3, IPEX
标记	PE
仪器	适用488nm, 532nm, 561nm激光器的流式细胞仪
亚型	Rat IgG2a, κ
克隆号	PCH101
推荐应用	流式检测
用量	5 μL /Test
纯化	亲和层析
储存液	含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃避光，切勿冻存

结果示例

图 - 人抗凝血染色 Anti-Human FoxP3, PE (F11FP302) 和 Anti-Human CD4, FITC (F11004B01) 的结果。已排除黏连细胞。

分子信息

概述人 FOXP3, IPEX 靶点信息

FOXP3 分子靶点信息概述

分子名：FOXP3, forkhead box P3
基因家族：Forkhead boxes
别名：JM2; XPID; AIID; PIDX; DIETER; SCURFIN
曾用名：IPEX
全称：immune dysregulation, polyendocrinopathy, enteropathy, X-linked

FOXP3 分子靶点综述

FoxP3蛋白是转录因子叉头家族的成员之一，表达于调节性T细胞(Regulatory T Cells, Treg)，其发育和功能受到叉头蛋白的影响。T细胞中FoxP3的异常表达会抑制其活性和细胞因子分泌。

人 Human FOXP3 分子靶点信息

分子名：FOXP3, forkhead box P3
别称：
- AIID
- DIETER
- forkhead box protein P3
- FOXP3delta7
- immune dysregulation, polyendocrinopathy, enteropathy, X-linked
- immunodeficiency, polyendocrinopathy, enteropathy, X-linked
- IPEX
- JM2
- MGC141961
- MGC141963
- PIDX
- scurfin
- XPID
基因序列：NCBI_Gene: 50943
蛋白序列：UniProtKB: Q9BZS1

人 Human FOXP3靶点分子功能（预测）

Enables several functions, including NFAT protein binding activity; enzyme binding activity; and protein homodimerization activity. Involved in several processes, including negative regulation of T cell activation; regulation of gene expression; and regulation of histone modification. Located in cytoplasm and nucleoplasm. Implicated in Human papillomavirus infectious disease; colorectal cancer; immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome; pulmonary tuberculosis; and type 1 diabetes mellitus. Biomarker of several diseases, including adult T-cell leukemia; anogenital venereal wart; chlamydia; liver disease (multiple); and tuberculosis (multiple).