F1104407

Anti-Human/Mouse, CD44, mFluor 450 (Clone: IM7) 检测试剂

¥640.00 – ¥1,472.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

分子靶点：CD44, MIC4, CSPG8
种属：人 (Human); 小鼠 (Mouse)
标记：mFlour 450
亚型：Rat IgG2b, κ
克隆号：IM7

在售SKU, F1104407, 70-F1104407-25, 70-F1104407-100

¥<\/span>1,472.00<\/bdi><\/span><\/span>","sku":"70-F1104407-100","variation_description":"","variation_id":19441,"variation_is_active":true,"variation_is_visible":true,"weight":"","weight_html":"N\/A"},{"attributes":{"attribute_size":"25T"},"availability_html":"","backorders_allowed":false,"dimensions":{"length":"","width":"","height":""},"dimensions_html":"N\/A","display_price":640,"display_regular_price":640,"image":{"title":"1656571413-fc-antibody.jpg","caption":"","url":"https:\/\/ecdn.liankebio.cn\/wp-content\/uploads\/1656571413-fc-antibody.jpg","alt":"","src":"https:\/\/ecdn.liankebio.cn\/wp-content\/uploads\/1656571413-fc-antibody.jpg","srcset":"https:\/\/www.liankebio.com\/wp-content\/uploads\/1656571413-fc-antibody.jpg 800w, https:\/\/www.liankebio.com\/wp-content\/uploads\/1656571413-fc-antibody-768x576.jpg 768w","sizes":"(max-width: 800px) 100vw, 800px","full_src":"https:\/\/ecdn.liankebio.cn\/wp-content\/uploads\/1656571413-fc-antibody.jpg","full_src_w":800,"full_src_h":600,"gallery_thumbnail_src":"https:\/\/ecdn.liankebio.cn\/wp-content\/uploads\/1656571413-fc-antibody-100x100.jpg","gallery_thumbnail_src_w":100,"gallery_thumbnail_src_h":100,"thumb_src":"https:\/\/ecdn.liankebio.cn\/wp-content\/uploads\/1656571413-fc-antibody.jpg","thumb_src_w":800,"thumb_src_h":600,"src_w":800,"src_h":600},"image_id":16568,"is_downloadable":false,"is_in_stock":true,"is_purchasable":true,"is_sold_individually":"no","is_virtual":false,"max_qty":"","min_qty":1,"price_html":"¥<\/span>640.00<\/bdi><\/span><\/span>","sku":"70-F1104407-25","variation_description":"","variation_id":19442,"variation_is_active":true,"variation_is_visible":true,"weight":"","weight_html":"N\/A"}]">

Size
库存号

文章目录[隐藏]

结果示例
分子信息
CD44 分子靶点信息概述
CD44 分子靶点综述

商品名	Anti-Human/Mouse, CD44, mFluor450 (Clone: IM7) 检测试剂
靶点	CD44, MIC4, CSPG8
标记	mFlour 450
仪器	适用405nm激光器的流式细胞仪
亚型	Rat IgG2b, κ
克隆号	IM7
推荐应用	流式检测
用量	5 μL /Test
纯化	亲和层析
储存液	含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃避光，切勿冻存

结果示例

图 - 人外周血进行染色，左图为Rat IgG2b, κ Isotype control, mFluor450的结果，右图为Anti-Human/Mouse CD44, mFluor450的结果。以单核细胞设门进行分析。

分子信息

概述

CD44 分子靶点信息概述

分子名：CD44, CD44 molecule (Indian blood group)
基因家族：Blood group antigens; CD molecules; Proteoglycans
别名：IN; MC56; Pgp1; CD44R; HCELL; CSPG8
曾用名：MIC4; MDU2; MDU3
全称：hematopoietic cell E- and L-selectin ligand; chondroitin sulfate proteoglycan 8; CD44 antigen (homing function and Indian blood group system)

CD44 分子靶点综述

成熟CD44蛋白无信号肽区，预计分子量37.2KD，经过翻译后糖基化等加工，CD44S蛋白质分子量可达80-90KD，这种蛋白质可与组织间隙中微静脉末端的高柱状内皮细胞表面的透明质酸结合，在淋巴细胞回归到粘膜和引流淋巴结中具有重要作用。变异性拼接外显子也有10个，位于第5、6组成型外显子之间，总长1245bp，含有变异性拼接外显子的CD44转录子称为CD44V。CD44V转录方式十分复杂，可连续性转录，也可跳跃性转录，参加拼接的外显子可多可少，从而使转录片段长短不一。