F2136603

Anti-Mouse CD366 (TIM-3)，APC (Clone: RMT3-23) 流式抗体 (新品)

¥1,008.00 – ¥2,224.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

分子靶点：CD366, TIM3, HAVCR2
种属：小鼠 (Mouse)
标记：APC
亚型：Rat IgG2a, κ
克隆号：RMT3-23

在售SKU, 70-AM36605-20, 70-AM36605-50, 70-AM36605-100, AM36605, 70-F2136603-25, 70-F2136603-100

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Size
库存号

文章目录[隐藏]

分子信息
HAVCR2 分子靶点信息概述
HAVCR2 分子靶点综述
- 小鼠 Mouse Havcr2 分子靶点信息
- 小鼠 Mouse Havcr2 靶点分子功能（预测）

商品名	Anti-Mouse CD366 (TIM-3)，APC (Clone: RMT3-23) 流式抗体
靶点	CD366, TIM3, HAVCR2
标记	APC
仪器	适用633nm激光器的流式细胞仪
亚型	Rat IgG2a, κ
克隆号	RMT3-23
推荐应用	流式检测
用量	5 μL /Test
纯化	亲和层析
储存液	含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃避光，切勿冻存

分子信息

概述小鼠 CD366, TIM3, HAVCR2 靶点信息

HAVCR2 分子靶点信息概述

分子名：HAVCR2, hepatitis A virus cellular receptor 2
基因家族：V-set domain containing
别名：Tim-3; TIM3; FLJ14428; TIMD3; CD366
全称：T-cell immunoglobulin mucin family member 3

HAVCR2 分子靶点综述

CD366，又名TIM-3，是一种I型跨膜糖蛋白，属于免疫球蛋白超家族内TIM家族。CD366在Th1、Th17、Treg、NK、NK-T、树突细胞、单核细胞、肥大细胞和巨噬细胞上表达，但不表达在B细胞和Th2细胞。CD366调节巨噬细胞活化并且是Th1细胞功能的负调节剂。

小鼠 Mouse Havcr2 分子靶点信息

分子名：Havcr2, hepatitis A virus cellular receptor 2
别称：
- T-cell immunoglobulin and mucin domain containing 3
- TIM-3
- Tim3
- Timd3
基因序列：NCBI_Gene: 171285
蛋白序列：

小鼠 Mouse Havcr2 靶点分子功能（预测）

Predicted to enable metal ion binding activity. Involved in several processes, including regulation of cytokine production; regulation of leukocyte activation; and toll-like receptor signaling pathway. Located in cell surface; early endosome; and immunological synapse. Is expressed in several structures, including dorsal aorta; gut; liver; lung; and reproductive system. Human ortholog(s) of this gene implicated in hepatocellular carcinoma and renal cell carcinoma. Orthologous to human HAVCR2 (hepatitis A virus cellular receptor 2).