EK115EG

EasyGo!™ Human IL-15 One-Step ELISA Kit检测试剂盒（酶联免疫吸附法）

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在售SKU:70-EK115EG-48, 70-EK115EG-96, EK115EG

分子靶点：IL15
种属：人
样本类型：血清，血浆，细胞培养上清及其他生物学样本
检测样本体积：50μL
灵敏度：1.40pg/mL
检测范围：7.81-500pg/mL
回收率：70%-130%

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ELISA试剂盒详细信息

商品名	EasyGo!™ Human IL-15 One-Step ELISA Kit检测试剂盒（酶联免疫吸附法）
种属	人
靶点	IL15
检测方法	双抗体夹心法
检测样本类型	血清，血浆，细胞培养上清及其他生物学样本
检测样本体积	50μL
灵敏度	1.40pg/mL
线性范围	7.81-500pg/mL
精密度	板内变异系数：< 10%;板间变异系数：< 10%
回收率	70%-130%
板式	96孔板，可拆
保存条件	2-8℃
运输条件	2-8℃冰袋运输
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性捕获抗体预包被在高亲和力的酶标板上，酶标板孔中预先加入辣根过氧化物酶标记的检测抗体微球。酶标板孔中加入标准品和待测样本，经过孵育，样本中存在的待测物质与捕获抗体和检测抗体结合。洗涤去除未结合的物质后，加入显色底物（TMB），避光显色。颜色反应的深浅与样本中待测物质的浓度成正比。加入终止液终止反应，在450nm波长 (参考波长570 - 630nm) 测定吸光度值。

文章目录[隐藏]

分子信息
IL15 分子靶点信息概述
IL15 分子靶点综述
- 人 Human IL15 分子靶点信息
- 人 Human IL15靶点分子功能（预测）

分子信息

概述人 IL15 靶点信息

IL15 分子靶点信息概述

分子名：IL15, interleukin 15
基因家族：Interleukins
别名：IL-15; MGC9721

IL15 分子靶点综述

白细胞介素15(IL-15)是一种促炎性蛋白，在中性粒细胞、树突状细胞和巨噬细胞的活化中起作用，对于NK细胞和CD8+T细胞的发育和生存是必不可少的。IL-15通过异三聚体受体信号激活Jak/Stat途径。虽然IL-15mRNA在许多细胞类型中表达，但是该分泌蛋白在生物样品中很少检测得到。最近的研究表明，IL-15滞留在胞内，只有当与其唯一的受体IL-15Rα形成复合物才能分泌到胞外。可溶性IL-15/IL-15R复合物由小鼠树突状细胞、成纤维细胞和巨噬细胞产生，它的结合活性比单独的IL-15提高10-100倍。

人 Human IL15 分子靶点信息

分子名：IL15, interleukin 15
别称：
- IL-15
- interleukin-15
- MGC9721
基因序列：NCBI_Gene: 3600
蛋白序列：UniProtKB: P40933

人 Human IL15靶点分子功能（预测）

Predicted to enable cytokine activity. Involved in several processes, including cell surface receptor signaling pathway; macrophage differentiation; and positive regulation of macromolecule metabolic process. Located in cytosol and nuclear speck. Implicated in aspergillosis; asthma; pleurisy; and type 1 diabetes mellitus. Biomarker of several diseases, including artery disease (multiple); brain infarction; lung disease (multiple); obesity; and viral infectious disease (multiple).