F3102501

Anti-Rat CD25 (OX39),FITC 流式抗体 (新品)

¥584.00 – ¥1,288.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

分子靶点：IL2RA, IL2R, CD25
种属：大鼠 (Rat)
标记：FITC
亚型：Mouse IgG1, κ
克隆号：OX39

在售SKU, 70-AR02501-20, 70-AR02501-50, 70-AR02501-100, AR02501, 70-F3102501-25, 70-F3102501-100

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Size
库存号

文章目录[隐藏]

分子信息
IL2RA 分子靶点信息概述
IL2RA 分子靶点综述
- 大鼠 Rat Il2ra 分子靶点信息
- 大鼠 Rat Il2ra 靶点分子功能（预测）

商品名	Anti-Rat CD25 (OX39),FITC 流式抗体
靶点	IL2RA, IL2R, CD25
标记	FITC
仪器	适用488nm激光器的流式细胞仪
亚型	Mouse IgG1, κ
克隆号	OX39
推荐应用	流式检测
用量	5 μL /Test
纯化	亲和层析
储存液	含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃避光，切勿冻存

图 - 图. SD 大鼠抗凝血染色 Anti-Rat CD25, FITC (AR02501)和 Anti-Rat CD4, APC(AR00405)的结果。已排除黏连细胞。

分子信息

概述大鼠 IL2RA, IL2R, CD25 靶点信息

IL2RA 分子靶点信息概述

分子名：IL2RA, interleukin 2 receptor subunit alpha
基因家族：CD molecules; Interleukin receptors; Sushi domain containing
别名：CD25
曾用名：IL2R; IDDM10
全称：insulin-dependent diabetes mellitus 10; interleukin 2 receptor, alpha

IL2RA 分子靶点综述

白细胞介素2受体(IL-2R)是一种在某些免疫细胞如淋巴细胞表面表达的异源三聚体蛋白，它可结合和应答细胞因子IL-2。IL-2R由三条链组成：一条α链(IL-2Rα/CD25)、一条β链(IL-2Rβ/CD122)和一条γ链(IL-2Rγ/CD132)。其中α链低亲和结合IL-2，而β和γ链组成的复合物中等亲和结合IL-2。IL-2及其受体主要通过直接作用于T细胞，从而在免疫系统、耐受性和免疫力中发挥重要作用。但是可溶性IL-2Rα(sIL-2Rα)的功能未知，因为它的低亲和力抑制了IL-2的结合。在任何情况下，体液中升高的sIL-2Rα水平与T、B细胞活化增加和免疫系统激活相关。监测血清中sIL-2Rα水平为一些病理状态如类风湿性关节炎、系统性红斑狼疮(SLE)、某些白血病和淋巴瘤提供更详细的见解。

大鼠 Rat Il2ra 分子靶点信息

分子名：Il2ra, interleukin 2 receptor subunit alpha
别称：
- IL-2 receptor alpha subunit
- IL-2 receptor subunit alpha
- IL-2-RA
- IL-2R subunit alpha
- IL2-RA
- IL2RAC
- interleukin 2 receptor, alpha
- interleukin 2 receptor, alpha chain
- interleukin-2 receptor alpha chain
- interleukin-2 receptor subunit alpha
基因序列：NCBI_Gene: 25704
蛋白序列：UniProtKB: P26897

大鼠 Rat Il2ra 靶点分子功能（预测）

Enables interleukin-2 receptor activity. Involved in inflammatory response to antigenic stimulus; positive regulation of T cell differentiation; and positive regulation of T cell proliferation. Located in cell surface. Used to study Korean hemorrhagic fever; asthma; and diabetes mellitus. Human ortholog(s) of this gene implicated in immunodeficiency 41; lymphopenia; multiple sclerosis; type 1 diabetes mellitus; and type 1 diabetes mellitus 10. Orthologous to human IL2RA (interleukin 2 receptor subunit alpha).