EK1165

Human BMP-7 ELISA Kit检测试剂盒（酶联免疫吸附法）

¥1,600.00 – ¥2,650.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

在售SKU:70-EK1165-48, 70-EK1165-96, EK1165

分子靶点：BMP7
种属：人
样本类型：血清、血浆、细胞培养上清及其他生物学样本
检测样本体积：血清、血浆样本20μL
灵敏度：2.06pg/mL
检测范围：7.81-500pg/mL
回收率：74%-120%

¥<\/span>1,600.00<\/bdi><\/span><\/span>","sku":"70-EK1165-48","variation_description":"","variation_id":8234,"variation_is_active":true,"variation_is_visible":true,"weight":"","weight_html":"N\/A"},{"attributes":{"attribute_size":"96T"},"availability_html":"","backorders_allowed":false,"dimensions":{"length":"","width":"","height":""},"dimensions_html":"N\/A","display_price":2650,"display_regular_price":2650,"image":{"title":"ELISA-1.jpg","caption":"","url":"https:\/\/ecdn.liankebio.cn\/wp-content\/uploads\/ELISA-1.jpg","alt":"","src":"https:\/\/ecdn.liankebio.cn\/wp-content\/uploads\/ELISA-1.jpg","srcset":"https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1.jpg 800w, https:\/\/www.liankebio.com\/wp-content\/uploads\/ELISA-1-768x576.jpg 768w","sizes":"(max-width: 800px) 100vw, 800px","full_src":"https:\/\/ecdn.liankebio.cn\/wp-content\/uploads\/ELISA-1.jpg","full_src_w":800,"full_src_h":600,"gallery_thumbnail_src":"https:\/\/ecdn.liankebio.cn\/wp-content\/uploads\/ELISA-1-100x100.jpg","gallery_thumbnail_src_w":100,"gallery_thumbnail_src_h":100,"thumb_src":"https:\/\/ecdn.liankebio.cn\/wp-content\/uploads\/ELISA-1.jpg","thumb_src_w":800,"thumb_src_h":600,"src_w":800,"src_h":600},"image_id":5986,"is_downloadable":false,"is_in_stock":true,"is_purchasable":true,"is_sold_individually":"no","is_virtual":false,"max_qty":"","min_qty":1,"price_html":"¥<\/span>2,650.00<\/bdi><\/span><\/span>","sku":"70-EK1165-96","variation_description":"","variation_id":8235,"variation_is_active":true,"variation_is_visible":true,"weight":"","weight_html":"N\/A"}]">

Size
库存号

ELISA试剂盒详细信息

商品名	Human BMP-7 ELISA Kit检测试剂盒（酶联免疫吸附法）
种属	人
靶点	BMP7
检测方法	双抗体夹心法
检测样本类型	血清、血浆、细胞培养上清及其他生物学样本
检测样本体积	血清、血浆样本20μL
灵敏度	2.06pg/mL
线性范围	7.81-500pg/mL
精密度	板内变异系数：4.4%-5.3%;板间变异系数：2.2%-4.9%
回收率	74%-120%
平均回收率	98%
板式	96孔板，可拆
保存条件	2-8℃保存。已拆开：标准品-20℃保存，其它4℃。
运输条件	2-8℃冰袋运输
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人BMP-7抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的BMP-7与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中BMP-7的浓度成正比。加入终止液终止反应，在450nm波长(参考波长570 - 630nm)测定吸光度值。

文章目录[隐藏]

分子信息
BMP7 分子靶点信息概述
BMP7 分子靶点综述
- 人 Human BMP7 分子靶点信息
- 人 Human BMP7靶点分子功能（预测）

分子信息

概述人 BMP7, OP-1 靶点信息

BMP7 分子靶点信息概述

分子名：BMP7, bone morphogenetic protein 7
基因家族：Bone morphogenetic proteins
别名：OP-1
全称：osteogenic protein 1

BMP7 分子靶点综述

骨形态发生蛋白7(BMP-7)是TGF-β超家族成员，表达于大脑、肾脏和膀胱。它在间充质细胞转化为骨骼和软骨中具有关键作用。BMP-7诱导SMAD1和SMAD5磷酸化，反过来又可诱导成骨基因的转录。在很多类型的细胞中，BMP-7处理足以诱导成骨细胞分化的所有遗传标志。BMP-7有可能治疗慢性肾病。在对FSH治疗效果不好的不孕不育中，BMP-7注射可能可以作为一种治疗方式。BMP-7也可能用于人类肥胖症的治疗。

人 Human BMP7 分子靶点信息

分子名：BMP7, bone morphogenetic protein 7
别称：
- BMP-7
- OP-1
- osteogenic protein 1
基因序列：NCBI_Gene: 655
蛋白序列：UniProtKB: P18075

人 Human BMP7靶点分子功能（预测）

Predicted to enable BMP receptor binding activity and cytokine activity. Involved in several processes, including regulation of gene expression; regulation of protein phosphorylation; and transmembrane receptor protein serine/threonine kinase signaling pathway. Acts upstream of or within negative regulation of neuron differentiation and neuron projection morphogenesis. Located in extracellular space. Implicated in prostate cancer. Biomarker of breast cancer; ovarian carcinoma; prostate cancer; and renal cell carcinoma.