EK198

Human CTGF ELISA Kit检测试剂盒（酶联免疫吸附法）

¥1,600.00 – ¥2,650.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

在售SKU:70-EK198-48, 70-EK198-96, EK198

分子靶点：CCN2
种属：人
样本类型：血清、血浆、细胞培养上清及其他生物学样本
检测样本体积：血清、血浆样本50μL
灵敏度：2.31pg/mL
检测范围：62.5-4000pg/mL
回收率：88%-115%

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Size
库存号

ELISA试剂盒详细信息

商品名	Human CTGF ELISA Kit检测试剂盒（酶联免疫吸附法）
种属	人
靶点	CCN2
检测方法	双抗体夹心法
检测样本类型	血清、血浆、细胞培养上清及其他生物学样本
检测样本体积	血清、血浆样本50μL
灵敏度	2.31pg/mL
线性范围	62.5-4000pg/mL
精密度	板内变异系数：4.9%-6.7%;板间变异系数：6.3%-7.5%
回收率	88%-115%
平均回收率	103%
板式	96孔板，可拆
保存条件	2-8℃保存。已拆开：标准品-20℃保存，其它4℃。
运输条件	2-8℃冰袋运输
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人CTGF抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的CTGF与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中CTGF的浓度成正比。加入终止液终止反应，在450nm波长(参考波长570 - 630nm)测定吸光度值。

文章目录[隐藏]

分子信息
CCN2 分子靶点信息概述
CCN2 分子靶点综述
- 人 Human CCN2 分子靶点信息
- 人 Human CCN2靶点分子功能（预测）

分子信息

概述人 CCN2, CTGF 靶点信息

CCN2 分子靶点信息概述

分子名：CCN2, cellular communication network factor 2
基因家族：Cellular communication network factors
别名：IGFBP8
曾用名：CTGF
全称：connective tissue growth factor

CCN2 分子靶点综述

结缔组织生长因子(CTGF)是CNN家族中的细胞基质蛋白。CTGF的胞外部分包括四个保守的、富含半胱氨酸的结构域：胰岛素样生长因子结合蛋白(IGFBP)结构域、血管性血友病C型重复序列(vWC)结构域、血小板反应蛋白1型重复序列(TSR)结构域以及含有半胱氨酸基元的C端结构域(CT)。CTGF在许多生物过程中发挥重要作用，包括细胞粘附、迁移、增殖、血管生成、骨骼发育和组织创伤修复。监测血清中CTGF水平可为一些病理情况如恶性肿瘤、糖尿病肾病、视网膜病变、纤维化、关节炎、胰腺癌和心血管疾病，提供更详细的见解。

人 Human CCN2 分子靶点信息

分子名：CCN2, cellular communication network factor 2
别称：
- CCN family member 2
- connective tissue growth factor
- CTGF
- HCS24
- hypertrophic chondrocyte-specific protein 24
- IBP-8
- IGF-binding protein 8
- IGFBP-8
- IGFBP8
- insulin-like growth factor-binding protein 8
- MGC102839
- NOV2
基因序列：NCBI_Gene: 1490
蛋白序列：UniProtKB: P29279

人 Human CCN2靶点分子功能（预测）

Enables protein C-terminus binding activity. Involved in positive regulation of MAPK cascade; positive regulation of cell differentiation; and positive regulation of stress fiber assembly. Colocalizes with collagen-containing extracellular matrix. Biomarker of ovarian cancer.