EK1264

Human CXCL2/GRO-β ELISA Kit 检测试剂盒（酶联免疫吸附法）

Name: Human CXCL2/GRO-β ELISA Kit 检测试剂盒（酶联免疫吸附法）
SKU: EK1264
Availability: InStock

¥1,600.00 – ¥2,650.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

在售SKU:70-EK1264-48, 70-EK1264-96, EK1264

分子靶点：CXCL2
种属：人
样本类型：血清、血浆、细胞培养上清及其他生物学样本
检测样本体积：血清、血浆样本10μL
灵敏度：0.53pg/mL
检测范围：4.69-300pg/mL
回收率：85%-110%

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Size
库存号

ELISA试剂盒详细信息

商品名	Human CXCL2/GRO-β ELISA Kit 检测试剂盒（酶联免疫吸附法）
种属	人
靶点	CXCL2
检测方法	双抗体夹心法
检测样本类型	血清、血浆、细胞培养上清及其他生物学样本
检测样本体积	血清、血浆样本10μL
灵敏度	0.53pg/mL
线性范围	4.69-300pg/mL
精密度	板内变异系数：4.8%-5.0%;板间变异系数：3.8%-4.7%
回收率	85%-110%
平均回收率	99%
板式	96孔板，可拆
保存条件	2-8℃保存。已拆开：标准品-20℃保存，其它4℃。
运输条件	2-8℃冰袋运输
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人GRO-β抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的GRO-β与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中GRO-β的浓度成正比。加入终止液终止反应，在450nm波长(参考波长570 - 630nm)测定吸光度值。

文章目录[隐藏]

分子信息
CXCL2 分子靶点信息概述
CXCL2 分子靶点综述
- 人 Human CXCL2 分子靶点信息
- 人 Human CXCL2靶点分子功能（预测）

分子信息

概述人 CXCL2, MIP-2a, GRO2, GROb 靶点信息

CXCL2 分子靶点信息概述

分子名：CXCL2, C-X-C motif chemokine ligand 2
基因家族：Chemokine ligands
别名：SCYB2; GROb; MIP-2a; MGSA-b; CINC-2a
曾用名：GRO2
全称：GRO2 oncogene; chemokine (C-X-C motif) ligand 2

CXCL2 分子靶点综述

人生长调节致癌基因β (GRO-β)也称为 CXCL2，是 CXC 蛋白趋化因子家族成员之一。GRO-β 在小鼠中也称为 MIP-2，在大鼠中称为 CINC-3。人 GRO-β由 107 个氨基酸(aa)构成，其分子量约为 11 kDa。GRO-β是由炎症部位的多种细胞(包括单核细胞和巨噬细胞)分泌，对粒细胞包括中性粒细胞具有趋化作用。GRO-β在炎症反应和损伤修复过程中起着重要作用。研究逐渐发现 GRO 为一种原癌基因。GRO-β作为表达产物在血管新生、肿瘤形成转移和肿瘤与免疫细胞相互作用中起到关键作用。

人 Human CXCL2 分子靶点信息

分子名：CXCL2, C-X-C motif chemokine ligand 2
别称：
- C-X-C motif chemokine 2
- chemokine (C-X-C motif) ligand 2
- CINC-2a
- gro-beta
- GRO2
- GRO2 oncogene
- GROb
- growth-regulated protein beta
- macrophage inflammatory protein 2-alpha
- melanoma growth stimulatory activity beta
- MGSA beta
- MGSA-b
- MIP-2a
- MIP2
- MIP2-alpha
- MIP2A
- SCYB2
基因序列：NCBI_Gene: 2920
蛋白序列：UniProtKB: P19875

人 Human CXCL2靶点分子功能（预测）

Predicted to enable CXCR chemokine receptor binding activity and chemokine activity. Involved in antimicrobial humoral immune response mediated by antimicrobial peptide; killing of cells of other organism; and response to molecule of bacterial origin. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Biomarker of COVID-19 and cystic fibrosis.