EK1145

Human Vitamin D BP ELISA Kit检测试剂盒（酶联免疫吸附法）

¥1,600.00 – ¥2,650.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

在售SKU:70-EK1145-48, 70-EK1145-96, EK1145

分子靶点：GC
种属：人
样本类型：血清、血浆、细胞培养上清及其他生物学样本
检测样本体积：血清、血浆样本5μL
灵敏度：40.15pg/mL
检测范围：78.13-5000pg/mL
回收率：95%-114%

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Size
库存号

ELISA试剂盒详细信息

商品名	Human Vitamin D BP ELISA Kit检测试剂盒（酶联免疫吸附法）
种属	人
靶点	GC
检测方法	双抗体夹心法
检测样本类型	血清、血浆、细胞培养上清及其他生物学样本
检测样本体积	血清、血浆样本5μL
灵敏度	40.15pg/mL
线性范围	78.13-5000pg/mL
精密度	板内变异系数：4.4%-5%;板间变异系数：4%-7.5%
回收率	95%-114%
平均回收率	105%
板式	96孔板，可拆
保存条件	2-8℃保存。已拆开：标准品-20℃保存，其它4℃。
运输条件	2-8℃冰袋运输
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性抗人VitaminDBP抗体预包被在高亲和力的酶标板上。酶标板孔中加入标准品、待测样本和生物素化的检测抗体，经过孵育，样本中存在的VitaminDBP与固相抗体和检测抗体结合。洗涤去除未结合的物质后，加入辣根过氧化物酶标记的链霉亲和素(Streptavidin-HRP)。洗涤后，加入显色底物TMB，避光显色。颜色反应的深浅与样本中VitaminDBP的浓度成正比。加入终止液终止反应，在450nm波长(参考波长570 - 630nm)测定吸光度值。

文章目录[隐藏]

分子信息
GC 分子靶点信息概述
GC 分子靶点综述
- 人 Human GC 分子靶点信息
- 人 Human GC靶点分子功能（预测）

分子信息

概述人 GC, VDBP, DBP 靶点信息

GC 分子靶点信息概述

分子名：GC, GC vitamin D binding protein
别名：DBP; VDBP; hDBP
全称：group-specific component (vitamin D binding protein); GC, vitamin D binding protein

GC 分子靶点综述

维生素D结合蛋白(VitaminDBP)也称为gc(组特异性成份)球蛋白，与人血清白蛋白和甲胎蛋白均属于白蛋白基因家族。它具有多种功能，存在于血浆、腹水、脑脊髓液和很多类型细胞的表面。它与维生素D及其代谢产物结合，将它们转运至靶组织。作为Gc蛋白衍生的巨噬细胞活化因子，VitaminDBP可用于癌症治疗，活化巨噬细胞抵抗肿瘤细胞。

人 Human GC 分子靶点信息

分子名：GC, GC vitamin D binding protein
别称：
- DBP
- DBP-maf
- DBP/GC
- epididymis secretory protein Li 51
- gc protein-derived macrophage activating factor
- gc-globulin
- Gc-MAF
- GcMAF
- GRD3
- group-specific component (vitamin D binding protein)
- HEL-S-51
- VDB
- VDBG
- VDBP
- vitamin D-binding alpha-globulin
- vitamin D-binding protein
- vitamin D-binding protein-macrophage activating factor
基因序列：NCBI_Gene: 2638
蛋白序列：UniProtKB: P02774

人 Human GC靶点分子功能（预测）

Enables actin binding activity and calcidiol binding activity. Predicted to be involved in vitamin transport. Predicted to act upstream of or within vitamin D metabolic process. Located in blood microparticle and extracellular exosome. Implicated in several diseases, including autoimmune disease (multiple); chronic obstructive pulmonary disease; hepatocellular carcinoma; human immunodeficiency virus infectious disease; and rheumatic fever. Biomarker of several diseases, including autoimmune disease (multiple); dengue disease; diabetic retinopathy; hepatic encephalopathy; and sciatic neuropathy.