F1103806

Anti-Human CD38, APC-Cy7 (Clone: HIT2) 流式抗体检测试剂

¥1,392.00 – ¥2,840.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

分子靶点：CD38
种属：人 (Human)
标记：APC-Cy7
亚型：Mouse IgG1, κ
克隆号：HIT2

在售SKU, F1103806, 70-F1103806-25, 70-F1103806-100

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Size
库存号

文章目录[隐藏]

结果示例
分子信息
CD38 分子靶点信息概述
CD38 分子靶点综述
- 人 Human CD38 分子靶点信息
- 人 Human CD38靶点分子功能（预测）

商品名	Anti-Human CD38, APC-Cy7 (Clone: HIT2) 检测试剂
靶点	CD38
标记	APC-Cy7
仪器	适用633nm激光器的流式细胞仪
亚型	Mouse IgG1, κ
克隆号	HIT2
推荐应用	流式检测
用量	5 μL /Test
纯化	亲和层析
储存液	含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃避光，切勿冻存

结果示例

图 - 人外周血进行染色，黑色线为Mouse IgG1, κ Isotype control, APC-Cy7的结果，红色线为Anti-Human CD38, APC-Cy7的结果。以单核细胞设门进行分析。

分子信息

概述人 CD38 靶点信息

CD38 分子靶点信息概述

分子名：CD38, CD38 molecule
基因家族：CD molecules
全称：ADP-ribosyl cyclase 1; NAD(+) nucleosidase; CD38 antigen (p45)

CD38 分子靶点综述

CD38是一个定位于膜上的糖蛋白，催化环腺苷二磷酸核糖的合成和降解，参与细胞粘附和信号转导。CD31是CD38的配体，当两者结合时，可导致骨髓B细胞凋亡，但可阻止扁桃体B细胞的凋亡，促进脾脏B细胞的增殖。正常表达于胸腺细胞、早期B和T细胞、生发中心B细胞、部分T细胞等。异常表达于骨髓瘤细胞、原发性渗出性淋巴瘤、一些慢性淋巴细胞白血病。

人 Human CD38 分子靶点信息

分子名：CD38, CD38 molecule
别称：
- 2'-phospho-ADP-ribosyl cyclase
- 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase
- 2'-phospho-cyclic-ADP-ribose transferase
- ADP-ribosyl cyclase 1
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
- ADPRC 1
- ADPRC1
- cADPr hydrolase 1
- cd38 antigen
- CD38 antigen (p45)
- cluster of differentiation 38
- cyclic ADP-ribose hydrolase 1
- ecto-nicotinamide adenine dinucleotide glycohydrolase
- NAD(+) nucleosidase
- T10
基因序列：NCBI_Gene: 952
蛋白序列：UniProtKB: P28907

人 Human CD38靶点分子功能（预测）

Predicted to enable NAD+ nucleosidase activity and phosphorus-oxygen lyase activity. Involved in several processes, including B cell receptor signaling pathway; positive regulation of B cell proliferation; and regulation of transcription, DNA-templated. Located in plasma membrane. Implicated in type 1 diabetes mellitus and type 2 diabetes mellitus.