F21004A02

Anti-Mouse CD4 (RM4-5)，PE 流式抗体 (新品)

¥128.00 – ¥264.00

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

分子靶点：CD4
种属：小鼠 (Mouse)
标记：PE
亚型：Rat IgG2a, κ
克隆号：RM4-5

在售SKU, 70-AM0040204-20, 70-AM0040204-50, 70-AM0040204-100, AM0040204, 70-F21004A02-25, 70-F21004A02-100

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Size
库存号

文章目录[隐藏]

结果示例
分子信息
CD4 分子靶点信息概述
CD4 分子靶点综述
- 小鼠 Mouse Cd4 分子靶点信息
- 小鼠 Mouse Cd4 靶点分子功能（预测）

商品名	Anti-Mouse CD4 (RM4-5)，PE 流式抗体
靶点	CD4
标记	PE
仪器	适用488nm, 532nm, 561nm激光器的流式细胞仪
亚型	Rat IgG2a, κ
克隆号	RM4-5
推荐应用	流式检测
用量	5 μL /Test
纯化	亲和层析
储存液	含 0.2% BSA 和 0.2% proclin 950 的磷酸盐缓冲液(pH7.2)
保存条件	2 - 8℃避光，切勿冻存

结果示例

图 - ICR 小鼠脾细胞染色 Anti-Mouse CD4, PE (F21004A02) 和 Anti-Mouse CD8α, APC (F2100803) 的结果。已排除粘连细胞。

分子信息

概述小鼠 CD4 靶点信息

CD4 分子靶点信息概述

分子名：CD4, CD4 molecule
基因家族：CD molecules; V-set domain containing; C2-set domain containing
全称：CD4 antigen (p55); T-cell surface glycoprotein CD4

CD4 分子靶点综述

CD4也称为T4，为55 kD的单链I型跨膜糖蛋白，表达于大部分胸腺细胞、T细胞亚群和单核/巨噬细胞。CD4作为免疫球蛋白超家族的一员，可识别与MHC II类分子结合的抗原，参与细胞-细胞互作、胸腺分化和信号传导。CD4是HIV的主要受体，可与HIV gp120结合。CD4与IL-16也有相互作用。

小鼠 Mouse Cd4 分子靶点信息

分子名：Cd4, CD4 antigen
别称：
- L3T4
- Ly-4
- lymphocyte antigen 4
基因序列：NCBI_Gene: 12504
蛋白序列：

小鼠 Mouse Cd4 靶点分子功能（预测）

Predicted to enable several functions, including interleukin-16 binding activity; interleukin-16 receptor activity; and protein homodimerization activity. Involved in helper T cell enhancement of adaptive immune response. Acts upstream of or within several processes, including defense response to Gram-negative bacterium; positive regulation of calcium-mediated signaling; and positive regulation of peptidyl-tyrosine phosphorylation. Located in endoplasmic reticulum; external side of plasma membrane; and membrane raft. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and liver and biliary system. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in immunodeficiency 79. Orthologous to human CD4 (CD4 molecule).