EK210REG

EasyGo!™ Mouse IL-10RB One-Step ELISA Kit检测试剂盒（酶联免疫吸附法）

查看活动价

因产品会迭代升级，具体实验步骤请按纸质版说明书操作

说明书

在售SKU:70-EK210REG-48, 70-EK210REG-96, EK210REG

分子靶点：IL10RB
种属：mouse-小鼠
样本类型：血清，血浆，细胞培养上清及其他生物学样本
检测样本体积：5μL
灵敏度：4.9pg/mL
检测范围：39.063-2500pg/mL
回收率：70%-130%

¥<\/span>2,190.00<\/bdi><\/span><\/span>","sku":"70-EK210REG-48","variation_description":"","variation_id":36772,"variation_is_active":true,"variation_is_visible":true,"weight":"","weight_html":"N\/A"},{"attributes":{"attribute_size":"96T"},"availability_html":"","backorders_allowed":false,"dimensions":{"length":"","width":"","height":""},"dimensions_html":"N\/A","display_price":3650,"display_regular_price":3650,"image":{"title":"EasyGo-1","caption":"","url":"https:\/\/ecdn.liankebio.cn\/wp-content\/uploads\/EasyGo-1.jpg","alt":"","src":"https:\/\/ecdn.liankebio.cn\/wp-content\/uploads\/EasyGo-1.jpg","srcset":"https:\/\/www.liankebio.com\/wp-content\/uploads\/EasyGo-1.jpg 800w, https:\/\/www.liankebio.com\/wp-content\/uploads\/EasyGo-1-768x576.jpg 768w","sizes":"(max-width: 800px) 100vw, 800px","full_src":"https:\/\/ecdn.liankebio.cn\/wp-content\/uploads\/EasyGo-1.jpg","full_src_w":800,"full_src_h":600,"gallery_thumbnail_src":"https:\/\/ecdn.liankebio.cn\/wp-content\/uploads\/EasyGo-1-100x100.jpg","gallery_thumbnail_src_w":100,"gallery_thumbnail_src_h":100,"thumb_src":"https:\/\/ecdn.liankebio.cn\/wp-content\/uploads\/EasyGo-1.jpg","thumb_src_w":800,"thumb_src_h":600,"src_w":800,"src_h":600},"image_id":18334,"is_downloadable":false,"is_in_stock":true,"is_purchasable":true,"is_sold_individually":"no","is_virtual":false,"max_qty":"","min_qty":1,"price_html":"¥<\/span>3,650.00<\/bdi><\/span><\/span>","sku":"70-EK210REG-96","variation_description":"","variation_id":36773,"variation_is_active":true,"variation_is_visible":true,"weight":"","weight_html":"N\/A"}]">

Size
库存号

ELISA试剂盒详细信息

商品名	EasyGo!™ Mouse IL-10RB One-Step ELISA Kit检测试剂盒（酶联免疫吸附法）
种属	mouse-小鼠
靶点	IL10RB
检测方法	双抗体夹心法
检测样本类型	血清，血浆，细胞培养上清及其他生物学样本
检测样本体积	5μL
灵敏度	4.9pg/mL
线性范围	39.063-2500pg/mL
精密度	板内变异系数：< 10%;板间变异系数：< 10%
回收率	70%-130%
板式	96孔板，可拆
保存条件	2-8℃
运输条件	blue ice
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性捕获抗体预包被在高亲和力的酶标板上，酶标板孔中预先加入辣根过氧化物酶标记的检测抗体微球。酶标板孔中加入标准品和待测样本，经过孵育，样本中存在的待测物质与捕获抗体和检测抗体结合。洗涤去除未结合的物质后，加入显色底物（TMB），避光显色。颜色反应的深浅与样本中待测物质的浓度成正比。加入终止液终止反应，在450nm波长 (参考波长570 - 630nm) 测定吸光度值。

文章目录[隐藏]

分子信息
IL10RB 分子靶点信息概述
IL10RB 分子靶点综述
- 小鼠 Mouse Il10rb 分子靶点信息
- 小鼠 Mouse Il10rb 靶点分子功能（预测）

分子信息

概述小鼠 IL1B, IL1-β, IL1F2 靶点信息

IL10RB 分子靶点信息概述

分子名：IL10RB, interleukin 10 receptor subunit beta
基因家族：Interleukin receptors; CD molecules
别名：CRF2-4; CDW210B; IL-10R2
曾用名：CRFB4; D21S58; D21S66
全称：interleukin 10 receptor, beta

IL10RB 分子靶点综述

白细胞介素10受体β亚基（IL10RB/IL-10RB），亦称为细胞因子受体家族2成员4、白细胞介素-10受体第二亚基、细胞因子受体家族II成员4，是构成白细胞介素-10受体的重要组分。该蛋白属于细胞因子受体家族，是形成功能性白细胞介素-10受体复合物所必需的辅助链。其与IL10RA蛋白的共同表达是实现IL-10诱导信号转导的必要条件。
IL10RB/IL-10RB的基因缺陷是导致25型炎症性肠病（IBD25）的病因。该病是一种具有复杂病因的慢性复发性胃肠道炎症，主要分为克罗恩病和溃疡性结肠炎两种临床类型。克罗恩病可累及从口腔至肛门的整个消化道，最常好发于回肠末端与结肠，其特征为透壁性、非连续性炎症，可伴发肉芽肿或肠道/肛周瘘管；而溃疡性结肠炎则表现为连续性炎症且局限于直肠与结肠黏膜层，通常不出现瘘管或肉芽肿。两种疾病均可能引发皮肤、眼部或关节等肠外炎症表现。

小鼠 Mouse Il10rb 分子靶点信息

分子名：Il10rb, interleukin 10 receptor, beta
别称：
- 6620401D04Rik
- AI528744
- CRF2-4
- Crfb4
- cytokine receptor family 2, member 4
- D16H21S58
- D21S58h
- DNA segment, Chr 16, human D21S58
- expressed sequence AI528744
- Il10r2
- RGD1560373
- RIKEN cDNA 6620401D04 gene
基因序列：NCBI_Gene: 16155
蛋白序列：

小鼠 Mouse Il10rb 靶点分子功能（预测）

Enables interleukin-10 receptor activity. Predicted to be involved in cytokine-mediated signaling pathway; positive regulation of cellular respiration; and positive regulation of receptor signaling pathway via JAK-STAT. Predicted to act upstream of or within interleukin-10-mediated signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in graft-versus-host disease; hepatitis B; and inflammatory bowel disease 25. Orthologous to human IL10RB (interleukin 10 receptor subunit beta).