EK2SA6EG

EasyGo!™ Mouse S100A6 One-Step ELISA Kit 检测试剂盒（酶联免疫吸附法）

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在售SKU, EK2SA6EG, 70-EK2SA6EG-96, 70-EK2SA6EG-48

分子靶点：S100A6
种属：小鼠
样本类型：血清，血浆，细胞培养上清及其他生物学样本
检测样本体积：20μL
灵敏度：30.48pg/mL
检测范围：93.75-6000pg/mL
回收率：70%-130%

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库存号

ELISA试剂盒详细信息

商品名	EasyGo!™ Mouse S100A6 One-Step ELISA Kit 检测试剂盒（酶联免疫吸附法）
种属	小鼠
靶点	S100A6
检测方法	双抗体夹心法
检测样本类型	血清，血浆，细胞培养上清及其他生物学样本
检测样本体积	20μL
灵敏度	30.48pg/mL
线性范围	93.75-6000pg/mL
精密度	板内变异系数：< 10%;板间变异系数：< 10%
回收率	70%-130%
板式	96孔板，可拆
保存条件	2-8℃
运输条件	2-8℃冰袋运输
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性捕获抗体预包被在高亲和力的酶标板上，酶标板孔中预先加入辣根过氧化物酶标记的检测抗体微球。酶标板孔中加入标准品和待测样本，经过孵育，样本中存在的待测物质与捕获抗体和检测抗体结合。洗涤去除未结合的物质后，加入显色底物（TMB），避光显色。颜色反应的深浅与样本中待测物质的浓度成正比。加入终止液终止反应，在450nm波长 (参考波长570 - 630nm) 测定吸光度值。

文章目录[隐藏]

分子信息
S100A6 分子靶点信息概述
S100A6 分子靶点综述
- 小鼠 Mouse S100a6 分子靶点信息
- 小鼠 Mouse S100a6 靶点分子功能（预测）

分子信息

概述小鼠 S100A6 靶点信息

S100A6 分子靶点信息概述

分子名：S100A6, S100 calcium binding protein A6
基因家族：S100 calcium binding proteins; EF-hand domain containing
别名：2A9; PRA; CABP
曾用名：CACY
全称：calcyclin; S100 calcium-binding protein A6 (calcyclin)

S100A6 分子靶点综述

S100蛋白是一类存在于脊椎动物中的低分子量蛋白质家族，其典型特征为具有两个EF手型钙结合结构域。该家族至少包含21种不同成员，其名称源于该类蛋白质在中性pH条件下能100%溶于硫酸铵溶液的特性。多数S100蛋白通过二硫键连接形成同源二聚体，通常存在于神经嵴来源细胞、软骨细胞、巨噬细胞、树突状细胞等细胞中。S100蛋白在细胞内外的多种功能活动中发挥作用，包括调节蛋白质磷酸化、转录因子活性、细胞骨架成分动态变化、酶活性、细胞生长与分化以及炎症反应等。S100A6（S100钙结合蛋白A6）作为该家族成员，参与催乳素分泌和胞吐作用过程。研究显示，S100A6的染色体易位和表达异常与黑色素瘤的发生发展密切相关。

小鼠 Mouse S100a6 分子靶点信息

分子名：S100a6, S100 calcium binding protein A6 (calcyclin)
别称：
- 2A9
- 5B10
- Cacy
- calcyclin
- CALCYCLIN
- PRA
基因序列：NCBI_Gene: 20200
蛋白序列：
- UniprotKB: P14069
- UniprotKB: Q545I9

小鼠 Mouse S100a6 靶点分子功能（预测）

Enables calcium ion binding activity and zinc ion binding activity. Predicted to be involved in monoatomic ion transmembrane transport. Located in collagen-containing extracellular matrix. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and trophectoderm. Orthologous to human S100A6 (S100 calcium binding protein A6).