EK216EG

EasyGo!™ Mouse IL-16 One-Step ELISA Kit 检测试剂盒（酶联免疫吸附法）

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在售SKU:70-EK216EG-48, 70-EK216EG-96, EK216EG

分子靶点：IL16
种属：小鼠
样本类型：血清，血浆，细胞培养上清及其他生物学样本
检测样本体积：10μL
灵敏度：2.27pg/mL
检测范围：3.13-200pg/mL
回收率：70%-130%

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库存号

ELISA试剂盒详细信息

商品名	EasyGo!™ Mouse IL-16 One-Step ELISA Kit 检测试剂盒（酶联免疫吸附法）
种属	小鼠
靶点	IL16
检测方法	双抗体夹心法
检测样本类型	血清，血浆，细胞培养上清及其他生物学样本
检测样本体积	10μL
灵敏度	2.27pg/mL
线性范围	3.13-200pg/mL
精密度	板内变异系数：< 10%;板间变异系数：< 10%
回收率	70%-130%
板式	96孔板，可拆
保存条件	2-8℃
运输条件	2-8℃冰袋运输
检测原理	本试剂盒采用双抗体夹心酶联免疫吸附检测技术。特异性捕获抗体预包被在高亲和力的酶标板上，酶标板孔中预先加入辣根过氧化物酶标记的检测抗体微球。酶标板孔中加入标准品和待测样本，经过孵育，样本中存在的待测物质与捕获抗体和检测抗体结合。洗涤去除未结合的物质后，加入显色底物（TMB），避光显色。颜色反应的深浅与样本中待测物质的浓度成正比。加入终止液终止反应，在450nm波长 (参考波长570 - 630nm) 测定吸光度值。

文章目录[隐藏]

分子信息
IL16 分子靶点信息概述
IL16 分子靶点综述
- 小鼠 Mouse Il16 分子靶点信息
- 小鼠 Mouse Il16 靶点分子功能（预测）

分子信息

概述小鼠 IL16, LCF 靶点信息

IL16 分子靶点信息概述

分子名：IL16, interleukin 16
基因家族：Interleukins; PDZ domain containing
别名：LCF; IL-16; prIL-16; HsT19289; FLJ42735; FLJ16806
全称：prointerleukin 16; lymphocyte chemoattractant factor; interleukin 16 (lymphocyte chemoattractant factor)

IL16 分子靶点综述

白细胞介素16(IL-16)是由多种细胞(包括淋巴细胞和一些上皮细胞)释放的细胞因子，是特定表达细胞表面分子CD4的免疫细胞的趋化物。IL-16最初被描述为是一种可吸引人类中活化的T细胞的因子，以前称之为淋巴细胞趋化因子(LCF)。此后，研究证明IL-16可招募和激活许多其它表达CD4分子的细胞，包括单核细胞、嗜酸性粒细胞和树突状细胞。该基因编码的蛋白是一种多效细胞因子，可作为趋化因子、T细胞活化的调节剂和HIV复制的抑制剂。这种细胞因子的信号过程受CD4调节。IL-16的表达与哮喘、类风湿性关节炎、系统性红斑狼疮、溃疡性结肠炎、过敏性皮炎和多发性硬化症的炎症过程有关。例如，IL-16的表达与哮喘上皮中浸润的CD4+T细胞的数量直接相关。

小鼠 Mouse Il16 分子靶点信息

分子名：Il16, interleukin 16
别称：
- 无
基因序列：NCBI_Gene: 16170
蛋白序列：

小鼠 Mouse Il16 靶点分子功能（预测）

Enables cytokine activity. Involved in cytokine-mediated signaling pathway. Acts upstream of or within several processes, including induction of positive chemotaxis; positive regulation of chemokine production; and positive regulation of neutrophil activation. Located in collagen-containing extracellular matrix. Is expressed in several structures, including foregut; jaw; limb; respiratory system; and vibrissa. Human ortholog(s) of this gene implicated in asthma and prostate cancer. Orthologous to human IL16 (interleukin 16).